垂体瘤术后继发完全性空蝶鞍的临床分析  

Clinical Analysis of Complete Empty Sella Secondary to Pituitary Adenoma Through Surgery

作　　者：王平[1] 丁长青 蔡嵩 张玉娜 WANG Ping;DING Changqing;CAI Song;ZHANG Yu'na(Department of Neurosurgery,Fengxian Hospital Affiliated to Nantong University(Fengxian People's Hospital of Jiangsu Province),Xuzhou,Jiangsu 221700;Department of Imaging,Fengxian Hospital Affiliated to Nantong University(Fengxian People's Hospital of Jiangsu Province),Xuzhou,Jiangsu 221700)

机构地区：[1]南通大学附属丰县医院(江苏省丰县人民医院)神经外科,江苏徐州221700 [2]南通大学附属丰县医院(江苏省丰县人民医院)影像科,江苏徐州221700

出　　处：《智慧健康》2022年第28期137-140,共4页Smart Healthcare

基　　金：江苏省卫生科研项目《MRI快速高性价比扫描系列研究》(项目编号:YG2014019)。

摘　　要：目的 探讨垂体瘤神经科术后继发完全性空蝶鞍的临床及影像学特征。方法 收集影像学及手术病理证实的100例垂体瘤患者的临床及MRI随访资料。对患者的性别、年龄及影像学MRI随访资料进行总结分析。结果 100例患者根据术后随访MRI诊断结果分为完全性空蝶鞍组(empty sella syndrome,ESS,n=34)及非空蝶鞍组(non empty sella syndrome,NESS,n=66)。两组在年龄及性别方面的差异无统计学意义(P>0.05);SESS组术前肿瘤平均大小高于NESS组,术后瘤灶残余较NESS组多,差异均有统计学意义(P<0.05)。ESS组在MRI上可见鞍区明显扩大,垂体形态正常信号消失,为脑脊液信号影取代,视交叉明显受压上抬。结论 术前垂体瘤灶较大者相对更易发生完全性空蝶鞍,MRI可明确诊断。Objective To investigate the clinical and imaging features of complete empty sella secondary to pituitary tumors through neurosurgery. Methods The clinical and MRI follow-up data of 100 patients with pituitary tumors confirmed by imaging and surgical pathology were collected.The gender, age and MRI follow-up data of the patients were summarized and analyzed. Results 100patients were divided into empty sella syndrome(ESS, n=34) and non-empty sella syndrome(NESS,n=66). There was no significant difference in age and gender between the two groups(P> 0.05). The average size of preoperative tumors in the SESS group was higher than that in the NESS group, and the residual tumors after surgery in the ESS group was higher than that in the NESS group, and the differences were statistically significant(P< 0.05). In the ESS group, the sellar area was significantly enlarged on MRI, the normal signal of the pituitary gland disappeared, and was replaced by the shadow signal of cerebrospinal fluid, and the optic chiasm was obviously compressed and lifted.Conclusion The patients with larger pituitary tumors before operation are more likely to have complete empty sella, which can be diagnosed clearly by MRI.

关 键 词：垂体瘤 空蝶鞍综合征 磁共振成像 

分 类 号：R736.4[医药卫生—肿瘤]