胶质淋巴系统功能障碍与早期帕金森病研究进展  

Dysfunction of lymphatic system and early Parkinson′s disease

作　　者：董照瀛 承欧梅[1] Zhaoying Dong;Oumei Cheng(Department of Neurology,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)

机构地区：[1]重庆医科大学附属第一医院神经内科,重庆400016

出　　处：《中华神经科杂志》2022年第11期1306-1310,共5页Chinese Journal of Neurology

摘　　要：胶质淋巴系统是脑脊液与脑间质液交换的运输途径, 是中枢神经系统的引流系统, 是全脑血管周围液体运输系统, 对脑内代谢废物的引流及排出有十分重要的作用。这一系统的功能在临床上可通过核磁共振中血管周围间隙的情况间接评价。帕金森病是一种较为常见的神经系统退行性疾病, 如能在该病早期甚至前驱期对血管周围间隙的变化情况进行动态观察, 可能有助于对疾病进展情况的把控。文中综述了胶质淋巴系统功能障碍与早期帕金森病的关系。Lymphatic system is the transportation way of cerebrospinal fluid and brain interstitial fluid exchange.And this system is a central nervous drainage system which plays an important role in drainaging and discharging of metabolic waste in the brain.The function of this system can be evaluated indirectly by the perivascular space on magnetic resonance imaging.Parkinson′s disease is a common neurodegenerative disorder.It may be helpful to control the progression of the disease if the changes of perivascular space can be dynamically observed in the early or even prodromal stage of the disease.This article reviews the relationship between lymphatic system disfunction and early stage of Parkinson′s disease.

关 键 词：淋巴系统 神经胶质 帕金森病 血管周围间隙 

分 类 号：R742.5[医药卫生—神经病学与精神病学]