基于“络病理论”探析冠脉无复流发病机制及中医辨治策略  

Pathogenesis of Coronary NRP and TCM Strategy in Syndrome Differentiation and Treatment Based on‘Collateral Disease Theory’

作　　者：李天舒 杨洁[2] 杨传华[2] LI Tianshu;YANG Jie;YANG Chuanhua(School of Chinese Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250014,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,China)

机构地区：[1]山东中医药大学中医学院,山东济南250014 [2]山东中医药大学附属医院,山东济南250014

出　　处：《中医药学报》2022年第12期82-85,共4页Acta Chinese Medicine and Pharmacology

基　　金：国家自然科学基金青年项目(81804061);济南市科技计划项目(201805078);泰山学者岗位建设资金资助项目(2018-35);山东省中医药科技发展计划(2019-0095)。

摘　　要：机体微循环障碍中的冠脉无复流现象是经皮冠状动脉介入术(PCI)术后常见的病理现象,严重影响了患者预后及生活质量。“络病理论”作为中医学理论体系的重要分支,近年来已趋于完善,形成了独立的体系。由于冠脉无复流的发生与络脉的发病有结构和功能上的相似性,故本文从“络病理论”出发,探究冠脉无复流的发生与络脉的联系,并从“络病”视角分析其发病机制可归结于“络脉不通”及“络脉不荣”,在治疗上以益气补虚通络和活血化瘀通络为基本治法,以期为中医药辨治此病提供思路。Coronary non-reflow phenomenon(NRP)among microcirculatory disorders within body is a common pathological phenomenon after percutaneous coronary intervention(PCI),which seriously affects the prognosis and life quality of the patients.As a significant branch of the theoretical system of Chinese medicine,the‘collateral disease theory’has been improved and formed an independent system in recent years.Since the occurrence of NRP in the coronary arteries has structural and functional similarities with the pathogenesis of collateral disease,this study explores the connection between the occurrence of NRP in the coronary arteries and collateral from the perspective of‘collateral disease’,and analyses its pathogenesis which can be attributed to‘obstruction of collateral’and‘malnourishment of collateral’,and uses the basic treatment method of benefiting Qi,tonifying deficiency and activating collateral and promoting blood circulation to remove blood stasis and activating collateral,in order to provide ideas for the differentiation and treatment of coronary NRP in TCM.

关 键 词：络病理论 冠脉无复流 发病机制 中医 辨证论治 

分 类 号：R22[医药卫生—中医基础理论]