Cocktails of defined chemical compounds:sufficient to induce totipotency in embryonic stem cells  

作　　者：Wilfried A.Kues Dharmendra Kumar 

机构地区：[1]Friedrich-Loeffler-Institut,Federal Research Institute for Animal Health,Biotechnology,Stem Cell Physiology,31535 Neustadt,Germany [2]Animal Physiology and Reproduction Division,ICAR-Central Institute for Research on Buffaloes,Hisar,Haryana 125001,India

出　　处：《Signal Transduction and Targeted Therapy》2022年第10期3630-3631,共2页信号转导与靶向治疗（英文）

摘　　要：In a recent work published in Nature,Hu et al.1 report that a cocktail of three small chemicals is sufficient to induce totipotency in murine embryonic stem(ES)cells.Earlier this year,two other groups identified different mixtures of chemicals,which also seem to do this job,2,3 taken together this opens a new approach to capture totipotency in vitro,and to understand the underlying pathways and their interaction.

关 键 词：interaction. al. INDUCE 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学]