18氟-氟代脱氧葡萄糖正电子发射体层摄影在癫痫持续状态患者中的运用  

Application of 18F-flurodeoxyglucose positron emission tomography in patients with status epilepticus

作　　者：陈亿忞 侯群[2] 蒋艳[2] Chen Yimin;Hou Qun;Jiang Yan(Department of Neurology,First Clinical Medical College of Zhejiang Chinese Medical University,Hangzhou 310053,China;Department of Neurology,First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine),Hangzhou 310006,China)

机构地区：[1]浙江中医药大学第一临床医学院神经内科,杭州310053 [2]浙江中医药大学附属第一医院(浙江省中医院)神经内科,杭州310006

出　　处：《中华神经科杂志》2022年第12期1431-1434,共4页Chinese Journal of Neurology

基　　金：浙江省卫生健康科技计划(2022KY228);浙江省中医药科技计划(2022ZB123)。

摘　　要：癫痫持续状态是一种神经系统急症,存在发病机制不清、治疗方案存争议、预后差等问题。近年随着18氟-氟代脱氧葡萄糖正电子发射体层摄影(18F-FDG PET)影像技术的发展,从分子代谢层面对癫痫持续状态有了进一步研究。文中就目前18F-FDG PET在癫痫持续状态患者中对病因及病情评估、神经电活动研究、致痫灶定位、预后预测等方面的运用进行综述。Status epilepticus is a neurological emergency with unknown pathogenesis,controversial treatment options,and poor prognosis.In recent years,with the development of 18F-flurodeoxyglucose positron emission tomography(18F-FDG PET)imaging technology,further studies on status epilepticus have been carried out from the perspective of molecular metabolism.This article reviews the current role of 18F-FDG PET in patients with status epilepticus on etiology,disease activity,electric activity,location of epileptogenic foci,and prognosis evaluation.

关 键 词：氟脱氧葡萄糖F18 正电子发射断层显像术 癫痫持续状态 癫痫 部分性 持续状态 新发难治性癫痫持续状态 发作期-发作间期连续体 

分 类 号：R742.1[医药卫生—神经病学与精神病学]