食管癌术后颈部食管胃吻合口瘘的相关影响因素分析  

Analysis of Related Factors of Cervical Esophagogastric Anastomotic Fistula after Esophageal Cancer

作　　者：靳凤梅 李转梅 JIN Fengmei;LI Zhumei(The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450000)

机构地区：[1]郑州大学第一附属医院,450000 [2]郑州大学第五附属医院,450000

出　　处：《实用癌症杂志》2023年第1期133-135,共3页The Practical Journal of Cancer

摘　　要：目的 探讨食管癌术后颈部食管胃吻合口瘘的相关影响因素。方法 回顾性分析182例食管癌患者临床资料,所有患者均进行食管癌根治术治疗。术后根据患者有无发生颈部食管胃吻合口瘘分为发生组与未发生组,统计2组一般资料,分析食管癌术后颈部食管胃吻合口瘘的相关影响因素。结果 182例食管癌患者中,术后有25例发生颈部食管胃吻合口瘘,发生率为13.74%(25/182)。发生组制作管状胃、糖尿病史、术后纤维支气管镜吸痰、术后肺部感染占比均高于未发生组,差异有统计学意义(P<0.05);2组基础资料、疾病情况、吸烟史、手术方法、吻合方法相比,差异无统计学意义(P>0.05)。Logistic回归分析:制作管状胃、糖尿病史、术后纤维支气管镜吸痰、术后肺部感染是食管癌术后发生颈部食管胃吻合口瘘的独立危险因素(P<0.05且OR≥1)。结论 食管癌术后吻合口瘘发生率较高,制作管状胃、糖尿病史、术后纤维支气管镜吸痰、术后肺部感染是其独立危险因素,临床需针对高危因素制定干预措施,以降低发生率。Objective To investigate the influencing factors of cervical oesophagogstastomotic fistula after esophageal cancer.Methods Clinical data of 182 esophageal cancer patients were retrospectively and all patients underwent radical esophageal cancer.After surgery, the patients were divided into occurrence and no groups according to whether the patients had cervical esophagogastric anastomotic fistula.The general data of two groups were counted and analyzed the relevant influencing factors of cervical oesophagogastric anastomosis fistula after esophageal cancer.Results Of the 182 patients with oesophageal cancer, 25 patients had postoperative cervical oesophageal-gastric anastomotic fistula, with an incidence of 13.74%(25/182).The proportion of tubular stomach, history of diabetes, postoperative bronchoscopic aspiration, and postoperative lung infection were higher than that of the untreated group, significant(P<0.05);basic data, disease, smoking history, surgery and anastomosis(P>0.05).Logistic regression analysis: making a tubular stomach, a history of diabetes, postoperative fibrobronchoscopic sputum aspiration, and postoperative lung infection were independent risk factors for cervical esophagogastric anastomotic fistula after esophageal cancer(P<0.05 and OR 1).Conclusion The incidence of anastomotic fistula after esophageal cancer, including tubular stomach, diabetes history, postoperative fiber bronchoscopic aspiration and postoperative lung infection are independent risk factors.Clinical interventions are needed to reduce the incidence.

关 键 词：食管癌手术 颈部食管胃吻合口瘘 影响因素 

分 类 号：R735.1[医药卫生—肿瘤]