全程同步加量调强放疗与后程缩野加量调强放疗在食管癌治疗中的价值对比分析  

Comparative Analysis of the Value of Full Synchronous IMRT and Late Shrinkage IMRT in the Treatment of Esophageal Cancer

作　　者：李倩[1] 许妍[1] 张智慧 LI Qian;XU Yan;ZHANG Zhihui(Henan People's Hospital,Zhengzhou,450003)

机构地区：[1]河南省人民医院,450003

出　　处：《实用癌症杂志》2023年第1期139-141,共3页The Practical Journal of Cancer

摘　　要：目的比较全程同步加量调强放疗(SIB-IMRT)与后程缩野加量调强放疗(LCB-IMRT)在食管癌治疗中的效果。方法选取96例食管癌患者,按随机数字表法分为2组,各48例。对照组给予LCB-IMRT,观察组予以SIB-IMRT,持续6周。对比2组临床疗效、照射剂量、不良反应。结果2组治疗总有效率相当,差异无统计学意义(P>0.05)。观察组左右肺、心脏、脊髓平均照射剂量、不良反应均低于对照组,差异有统计学意义(P<0.05)。结论SIB-IMRT与LCB-IMRT均能有效缩减食管癌患者病灶,缓解临床症状,但SIB-IMRT照射剂量分布更均匀、准确,不良反应少,值得应用。Objective To compare the effect of whole-course synchronous plus intensity modulated radiotherapy(SIB-IMRT)and late reduced field plus intensity modulated radiotherapy(LCB-IMRT)in the treatment of esophageal cancer.Methods 96 patients with esophageal cancer were divided into 2 groups,each with 48 patients.The control group received LCB-IMRT and the observation group received SIB-IMRT for 6 weeks.Clinical efficacy,irradiation dose,and adverse effects were compared between the 2 groups.Results The overall response rates of the 2 groups were comparable,there had no statistically significant difference(P>0.05).The mean irradiation dose and adverse effects of the left and right lung,heart and spinal cord were lower than that of the control group,there had statistically significant difference(P<0.05).Conclusion Both SIB-IMRT and LCB-IMRT can effectively reduce the lesions and relieve the clinical symptoms,but SIB-IMRT irradiation dose distribution is more uniform and accurate,with less adverse effects.

关 键 词：食管癌 全程同步加量调强放疗 后程缩野加量调强放疗 不良反应 

分 类 号：R735.1[医药卫生—肿瘤]