妊娠滋养细胞肿瘤生育力保护研究现状  

Research progress of fertility protection in gestational trophoblastic tumors

作　　者：赵峻[1] 向阳[1] ZHAO Jun;XIANG Yang(Department of Obstetrics and Gynecology,National Clinical Research Center for Obstetric&Gynecologic Diseases,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China)

机构地区：[1]中国医学科学院,北京协和医学院,北京协和医院妇产科,北京100730

出　　处：《中国实用妇科与产科杂志》2022年第11期1079-1083,共5页Chinese Journal of Practical Gynecology and Obstetrics

基　　金：国家自然科学基金(81971475)。

摘　　要：妊娠滋养细胞肿瘤(gestational trophoblastic neoplasms,GTN)包括侵蚀性葡萄胎、绒毛膜癌、胎盘部位滋养细胞肿瘤和上皮样滋养细胞肿瘤。GTN多发生于育龄妇女,因此,治疗的同时保留患者的生育力尤为重要。文章阐述了保留生育力治疗GTN的方法,如全身静脉化疗或动脉插管化疗、动脉栓塞治疗、保守性手术、免疫治疗等,并总结保留生育力治疗后的妊娠结局等相关问题。Gestational trophoblastic neoplasms(GTNs)include invasive hydatidiform mole,choriocarcinoma,placental site trophoblastic tumors and epithelioid trophoblastic tumors.GTN mostly occurs in women of child-bearing age,so it is particularly important to preserve the fertility of patients.This paper expounded the methods of fertility-sparing treatments for GTN,such as systemic intravenous chemotherapy or arterial intubation chemotherapy,arterial embolization,conservative surgery,and immunotherapy.The pregnancy outcomes after fertility-preserving treatment were summarized.

关 键 词：妊娠滋养细胞肿瘤 保留生育力治疗 化疗 手术 免疫治疗 

分 类 号：R737.3[医药卫生—肿瘤]