经鼻-空肠肠内营养支持对重症急性胰腺炎患者胃肠道保护及营养状态改善效果的观察  

Effects of enteral nutrition support via nasal-jejunal tube on gastrointestinal protection and nutritional status improvement in patients with severe acute pancreatitis:an observation study

作　　者：梅雪 沈刘艳 MEI Xue;SHEN Liuyan(Department of Critical Care Medicine,No.904 Hospital of Joint Logistics Support Force,the Chinese People's Liberation Army,Wuxi 214000,Jiangsu Province,China)

机构地区：[1]中国人民解放军联勤保障部队第九〇四医院重症医学科,江苏省无锡市214000

出　　处：《内科》2022年第5期510-513,534,共5页Internal Medicine

摘　　要：目的探讨经鼻-空肠肠内营养支持对重症急性胰腺炎患者胃肠道保护和营养状态的改善效果。方法回顾性分析98例重症急性胰腺炎患者的资料,根据营养支持方法将其分作两组,每组49例。对照组接受肠外营养支持,观察组接受经鼻-空肠肠内营养支持。比较两组治疗前后胃肠道功能和营养状态,以及住院期间并发症发生情况。结果停止营养支持后第7天时,观察组血清二胺氧化酶、D-乳酸水平均低于对照组,腹泻腹胀缓解、恶心呕吐缓解、肠鸣音恢复、肛门排气和经口进食恢复的时间均短于对照组,血清白蛋白、前白蛋白和转铁蛋白水平均高于对照组(均P<0.05)。住院期间,观察组的并发症发生率(4.08%)低于对照组(16.33%)(P<0.05)。结论经鼻-空肠肠内营养支持可有效地保护重症急性胰腺炎患者的胃肠道,促进其胃肠道功能尽早恢复,并进一步改善患者营养状态,降低并发症发生率。Objective To investigate the effects of enteral nutrition support via nasal-jejunal tube on gastrointestinal protection and nutritional status improvement in patients with severe acute pancreatitis.Methods The data of 98 patients with severe acute pancreatitis were retrospectively analyzed,and they were divided into two groups according to nutritional support method,with 49 cases in each group.The control group received parenteral nutrition support,and the observation group received enteral nutrition support via nasal-jejunal tube.The gastrointestinal function and nutritional status before and after the treatment,as well as the incidence of complications during hospitalization,were compared between the two groups.Results On the 7th day after stopping nutritional support,the serum diamine oxidase and D-lactic acid levels in the observation group were lower than those in the control group,and the time for diarrhea and abdominal distension release,nausea and vomiting release,bowel sounds recovery,anal exhaust recovery,and oral feeding recovery were shorter than those in the control group,while the serum albumin,prealbumin and transferrin levels were higher than those in the control group(all P<0.05).During hospitalization,the incidence of complications in the observation group(4.08%)was lower than that in the control group(16.33%)(P<0.05).Conclusion Enteral nutrition support via nasal-jejunal tube can effectively protect the gastrointestinal tract of patients with severe acute pancreatitis,promote the early recovery of gastrointestinal function,further improve their nutritional status and reduce the incidence of complications.

关 键 词：经鼻-空肠肠内营养支持 重症急性胰腺炎 并发症 胃肠道 营养状态 

分 类 号：R576[医药卫生—消化系统]