血液系统恶性肿瘤患者中心静脉导管相关性血栓的分析  

Analysis of central venous catheter-related thrombosis in patients with hematological malignancies

作　　者：陈洁[1] 王利灵 蒋培琴[1] 丰青[2] Chen Jie;Wang Liling;Jiang Peiqin;Feng Qing(Department of Hematology,Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025;Department of Nursing,Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025)

机构地区：[1]上海交通大学医学院附属瑞金医院血液科,上海200025 [2]上海交通大学医学院附属瑞金医院护理部,上海200025

出　　处：《现代科学仪器》2022年第6期182-185,共4页Modern Scientific Instruments

摘　　要：目的:探讨血液系统恶性肿瘤患者中心静脉导管相关性血栓(CRT)的发生率和相关危险因素。方法:纳入近3年接受置管化疗的血液系统恶性肿瘤患者,分析CRT发生原因。结果:CRT发生率为6.80%;CRT组的BMI偏高比例、合并静脉血栓史比例、PICC置入比例、左侧置管比例和置管前D-二聚体升高比例均显著高于对照组(P<0.05);多因素Logistic回归分析显示BMI>25kg/m2、PICC和D-二聚体>0.5mg/L是患者发生CRT的独立危险因素。结论:血液系统恶性肿瘤患者CRT发生率较高,超重、PICC和置管前D-二聚体升高均是CRT发生的独立危险因素。Objective:to investigate the incidence and risk factors of central venous catheter-related thrombosis(CRT)in patients with hematological malignancies.Methods:patients with hematological malignancies treated with catheterization chemotherapy in recent 3 years were included.The causes of CRT were analyzed.Results:the overall incidence of CRT was 6.80%.The proportion of increased BMI,the history of venous thrombosis,PICC implantation,left catheterization and the high D-dimer before catheterization in CRT group were significantly higher than those in the control group(P<0.05).Multivariate logistic regression analysis showed that BMI>25kg/m^(2),PICC and D-dimer>0.5mg/L were independent risk factors for CRT.Conclusion:the incidence rate of CRT in patients with hematological malignancies is high.Overweight,PICC and the rise of D-dimer before catheterization are independent risk factors for CRT.

关 键 词：血液系统恶性肿瘤 中心静脉导管相关性血栓 发生率 危险因素 

分 类 号：R730[医药卫生—肿瘤]