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作 者:中华医学会眼科学分会神经眼科学组 魏世辉[2] 孙传宾[3] Neuro-ophthalmology Group of Ophthalmology Branch of Chinese Medical Association;Wei Shihui
机构地区:[1]不详 [2]解放军总医院眼科医学部 [3]浙江大学医学院附属第二医院
出 处:《中华眼底病杂志》2022年第12期955-962,共8页Chinese Journal of Ocular Fundus Diseases
基 金:国家重点研发计划项目(2018YFE0113900);国家自然科学基金面上项目(81870662)。
摘 要:浸润性视神经病变(ION)是以视神经及其鞘内肿瘤细胞或炎症细胞浸润为特征的视神经病变。该病较为罕见,尤其是恶性肿瘤浸润或转移引起的ION,极易误诊为视神经周围炎或视神经炎,从而延误治疗,并带来糖皮质激素治疗副作用相关风险。目前国内眼科医师对ION的认识尚存在不足,临床误诊和漏诊率较高,针对ION的诊断和治疗尚未形成系统的规范化指导意见。因此,为了规范ION的诊治,中华医学会眼科学分会神经眼科学组组织专家,结合国内外研究经验,经过反复讨论,针对ION的定义、诊断和治疗提出规范化意见,以期指导ION的临床诊疗工作,并为相关研究提供依据。Infiltrative optic neuropathy(ION)is characterized by the infiltration of tumor cells or inflammatory cells in the optic nerve and its sheath.ION is rare in clinic practice,and ION caused by direct infiltration or metastasis of malignant tumors is easily misdiagnosed as optic perineuritis or optic neuritis,which means delayed proper treatment and makes patients risking possible side effects of steroid therapy.Currently,ophthalmologists are lack of sufficient knowledge about ION,which contributes to the high rate of misdiagnosis and missed diagnosis of ION in clinical practice.The diagnosis and treatment of ION have not yet formed systematic standardized guidelines.Therefore,Neuro-ophthalmology Group of Ophthalmology Branch of Chinese Medical Association organized experts to propose consenus of opinions on definition,diagnosis and treatment of ION,which helps to guide clinical diagnosis and treatment of ION,as well as basic researches about ION.
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