九龙藤茎化学成分和抑菌活性研究  

The chemical constitution and antibacterial activity of Bauhinia championii(Benth.)Benth

作　　者：杨彩霞[1] 韩冰洋 姚书蓉 苏瀛鹏 YANG Cai-xia;HAN Bing-yang;YAO Shu-rong;SU Ying-peng(Key Laboratory of Polymer Materials of Gansu Province,Key Laboratory of Eco-Envirement Related Polymer Materials of Ministry of Education,College of Chemistry and Chemical Engineering,Northwest Normal University,Lanzhou 730070,Gansu,China)

机构地区：[1]西北师范大学化学化工学院,甘肃省高分子材料重点实验室,生态环境相关高分子材料教育部重点实验室,甘肃兰州730070

出　　处：《西北师范大学学报（自然科学版）》2022年第5期71-76,共6页Journal of Northwest Normal University(Natural Science)

基　　金：甘肃省自然科学基金资助项目(21JRIRA232)。

摘　　要：从九龙藤茎部的乙醇提取物中分离得到了15个非黄酮类化合物,经IR,1HNMR,13 CNMR等分析法表征,结合标样对照,鉴定了它们的结构,分别为:β-谷甾醇(1)、正三十烷(2)、正六十烷(3)、羽扇豆醇(4)、β-香树脂醇(5)、计曼尼醇(6)、cameroonan-7α-ol(7)、silphiperfolane-3,5,6-trio1(8)、齐墩果酸(9)、β-胡萝卜苷(10)、没食子酸(11)、3,4-二羟基苯甲酸乙酯(12)、阿魏酸(13)、3,4-二甲氧基-5-羟基苯甲酸(14)和4-羟基-3-甲氧基苯甲酸(15).其中,化合物3~4,7~9和12~14为首次从该植物中得到.抑菌实验结果表明,该植物的乙酸乙酯提纯部分和正丁醇提纯部分均具有较好的抑菌活性.Fifteen compounds were isolated from the stem of Bauhinia championii(Benth.)Benth.Based on the spectral analysis,such as IR,1HNMR and 13 CNMR,and compared with standard sample,these compounds were identified asβ-sitosterol(1),n-triacontane(2),n-hexacontane(3),lupeol(4),β-amyrin(5),germanicol(6),cameroonan-7α-ol(7),silphiperfolane-3,5,6-trio1(8),oleanolic acid(9),β-daucosterol(10),gallic acid(11),3,4-dihydroxyethylbenzoate(12),ferulicacid(13),3,4-dimethoxy-5-hydroxybenzoic acid(14)and 4-hydroxy-3-methoxy benzoic acid(15).In these compounds,3~4,7~9 and 12~14 were obtained from the plant for the first time.In addition,the results of the experiment of antibacterial activity indicated that the AcOEt and n-BuOH extracts of this plant have better antibacterial activity.

关 键 词：豆科 九龙藤 茎部 化学成分 抑菌活性 

分 类 号：R284.1[医药卫生—中药学]