细针穿刺细胞学检查与粗针活检组织学检查在甲状腺恶性结节诊断中的效能比较  

Comparison of efficacies of fine needle aspiration cytology and core needle biopsy in diagnosis of malignant thyroid nodules

作　　者：郭力硕 袁征[1] 张文娟 GUO Lishuo;YUAN Zheng;ZHANG Wenjuan(Department of Pathology of Nanyang Central Hospital,Nanyang 473000 Henan,China)

机构地区：[1]南阳市中心医院病理科,河南南阳473000

出　　处：《中国民康医学》2022年第24期121-123,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:比较细针穿刺细胞学检查与粗针活检组织学检查在甲状腺恶性结节诊断中的效能。方法:选取2019年10月至2021年11月本院收治的80例甲状腺结节患者的84个结节进行前瞻性研究。所有患者均行粗针活检组织学检查与细针穿刺细胞学检查,以病理检查结果为金标准,比较两种检查诊断甲状腺恶性结节的灵敏度、特异度、准确度和不同直径结节诊断准确度。结果:金标准结果显示,80例疑似甲状腺恶性结节患者的84个结节中,恶性53个,良性31个;细针穿刺细胞学检查诊断恶性51个,良性33个;粗针活检组织学检查诊断恶性51个,良性33个;细针穿刺细胞学检查诊断的灵敏度、特异度、准确度与粗针活检组织学检查诊断比较,差异均无统计学意义(P>0.05);结节直径≥1.0 cm,粗针活检组织学检查诊断准确度为94.34%,高于细针穿刺细胞学检查诊断的81.13%,差异有统计学意义(P<0.05);结节直径<1.0 cm,细针穿刺细胞学检查诊断的准确度与粗针活检组织学检查诊断的准确度比较,差异无统计学意义(P>0.05)。结论:粗针活检组织学、细针穿刺细胞学对甲状腺恶性结节诊断中可相互补充,两者均可有效辨别甲状腺恶性结节,但对于直径≥1.0 cm结节,粗针活检组织学检查准确度更高。Objective:To compare efficacies of fine needle aspiration cytology and core needle biopsy in diagnosis of malignant thyroid nodules.Methods:84 nodules from 80 patients with thyroid nodules admitted to this hospital from October 2019 to November 2021 were selected for prospective study.All patients underwent core needle biopsy and fine needle aspiration cytology examinations.Taking the pathological examination results as the gold standard,the sensitivity,specificity,accuracy and diagnostic accuracy in the diagnosis of the nodules with different diameters were compared between the two examinations.Results:The gold standard results showed among the 84 nodules in the 80 patients with suspected malignant thyroid nodules,53 were malignant and 31 were benign.The fine needle aspiration cytology showed that 46 were malignant and 26 were benign;and the core needle biopsy showed that 48 were malignant and 28 were benign.There were no significant differences in the sensitivity,specificity and accuracy between fine needle aspiration cytology and core needle biopsy(P>0.05).When the diameter of the nodules was≥1.0 cm,the diagnostic accuracy of core needle biopsy was 94.34%,which was significantly higher than the fine needle aspiration cytology of 81.13%(P<0.05).When the diameter of nodules was<1.0 cm,there was no significant difference in the accuracy between the two examinations(P>0.05).Conclusions:Core needle biopsy histology and fine needle aspiration cytology can complement each other in the diagnosis of malignant thyroid nodules.Both can effectively identify the malignant thyroid nodules.However,for the nodules with diameter≥1.0 cm,the accuracy of core needle biopsy is higher.

关 键 词：甲状腺 恶性结节 粗针活检组织学 细针穿刺细胞学 病理检查 

分 类 号：R736.1[医药卫生—肿瘤]