不同级别胰腺内分泌肿瘤的CT、MRI特征与临床病理特征对照分析  

Comparative Analysis between CT, MRI Features and Clinicopathological Features in Different Grades of Pancreatic Neuroendocrine Neoplasms

作　　者：张亚斌 陈殿森[1] ZHANG Ya-bin;CHEN Dian-sen(The First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,Henan Province,China)

机构地区：[1]河南科技大学第一附属医院,河南洛阳471000

出　　处：《中国CT和MRI杂志》2023年第1期109-112,共4页Chinese Journal of CT and MRI

基　　金：河南省省直医疗机构服务能力提升工程建设项目(2017-51);洛阳市医疗卫生科研专项(2001027A)。

摘　　要：目的 对照分析不同级别胰腺内分泌肿瘤(PNENs)的X射线断层成像(CT)、磁共振(MRI)特征与临床病理特征。方法 选取2019年9月至2020年9月于本院收治的PNENs患者86例,均行CT和MRI检查,以病理检测为标准,比较不同分级的PNENs患者CT、MRI特征与临床病理特征,比较两种检查方式对PNENs的检出率,采用ROC曲线分析两种方法对不同分级PNENs的诊断效能。结果 不同分级PNENs患者病发部位比较,差异有统计学意义(P<0.05);CT检测结果中,不同分级患者的肿瘤直径、病灶边缘、形状和远端转移、胰管扩张、囊变坏死、CT强化值比较,差异有统计学意义(P<0.05);MRI检测结果,不同分级患者的肿瘤直径、病灶边缘、形状和远端转移、胰管扩张、囊变坏死、MRI高信号比较,差异有统计学意义(P<0.05);两种检测手段检查PNENs的检出率比较,差异无统计学意义(P>0.05);CT联合MRI检测低、高级别PNENs的诊断效能为0.879,灵敏度、特异度分别为85.71%、90.00%,明显优于单一检测(P<0.05)。结论 不同级别的PNENs患者,其CT、MRI影像学特征均有明显差异,CT、MRI均能有效评估PNENs分级,联合检查能明显提高对低、高级别PNENs患者的诊断效能。Objective To comparatively analyze the features between computed axial tomography(CT), magnetic resonance imaging(MRI) and clinical pathology in different grades of pancreatic neuroendocrine neoplasms(PNENs). Methods A total of 86 PNENs patients admitted to the hospital between September 2019 and September 2020 were enrolled. All underwent CT and MRI examinations. Taking pathological examination as the golden standard, features between CT, MRI and clinical pathology in patients with different grades of PNENs were compared. The detection rates of PNENs by the two methods were compared. The diagnostic efficiency of the two methods for different grades of PNENs was analyzed by ROC curves. Results The differences in sites of lesions among patients with different grades of PNENs were statistically significant(P<0.05). In CT examination results, the differences in tumor diameter, edge, shape and distal metastasis of lesions, pancreatic duct dilation, cystic necrosis and CT enhancement value among patients with different grades of PNENs were statistically significant(P<0.05). In MRI examination results, the differences in tumor diameter, edge, shape and distal metastasis of lesions, pancreatic duct dilatation, cystic necrosis and MRI high-signal among patients with different grades of PNENs were statistically significant(P<0.05). The difference in the detection rate of PNENs by the two methods was not statistically significant(P>0.05). The diagnostic efficiency, sensitivity and specificity of CT combined with MRI for low-grade and high-grade PNENs were 0.879, 85.71% and 90.00%, respectively, significantly better than those of single index(Pa<0.05). Conclusion There are significant differences in CT and MRI features in patients with different grades of PNENs. Both CT and MRI can effectively evaluate PNENs grading, and the combined examination can significantly improve the diagnostic efficiency for patients with low-grade and high-grade PNENs.

关 键 词：胰腺内分泌肿瘤 CT MRI 临床病理特征 

分 类 号：R735.9[医药卫生—肿瘤]