腹腔镜根治性宫颈切除术治疗早期宫颈癌的临床疗效  

Clinical Efficacy of Laparoscopic Radical Cervical Resection for Early Cervical Cancer

作　　者：陈影 CHEN Ying(Changtu County Central Hospital,Liaoning Tieling 112599)

机构地区：[1]昌图县中心医院,辽宁铁岭112599

出　　处：《中国医疗器械信息》2022年第23期129-131,共3页China Medical Device Information

摘　　要：目的:分析腹腔镜根治性宫颈切除术治疗早期宫颈癌的临床疗效。方法:选择2019年9月~2020年9月于本院诊治的120例宫颈癌患者,按抽签方式将其分为对照组和观察组,每组60例。对照组给予经腹根治性子宫切除术治疗,观察组给予经腹腔镜根治性宫颈切除术治疗,观察并记录两组临床指标、并发症发生率以及手术前后血清IgG、IgM、IgA、SCC、CA125、IL-6水平变化情况。结果:观察组各项临床指标均低于对照组,差异有统计学意义(P<0.05);观察组与对照组的并发症发生率相比,差异无统计学意义(P>0.05);两组患者术后血清IgG、IgM、IgA、SCC、CA125、IL-6水平较术前均有显著改善,除IgA、SCC、CA125水平比较差异无统计学意义外,观察组IgG、IgM水平高于对照组,IL-6水平低于对照组,差异有统计学意义(P<0.05);术后随访3个月,观察组临床疗效优良率明显高于对照组,差异有统计学意义(P<0.05)。结论:对早期宫颈癌患者实施经腹腔镜根治性宫颈切除术治疗安全可行,且术中失血量少,术后恢复快,人体免疫功能影响小,术后患者临床疗效较好。Objective:To analyze the clinical effect of laparoscopic radical hysterectomy in the treatment of early cervical cancer.Methods:120 patients with cervical cancer treated in our hospital from September 2019 to September 2020 were selected and divided into control group and observation group by drawing lots,with 60 cases in each group.The control group was given abdominal radical hysterectomy,and the observation group was given laparoscopic radical hysterectomy.The clinical indicators,incidence of complications and changes of serum IgG,IgM,IgA,SCC,CA125,and IL-6 levels before and after operation were observed and recorded.Results:The clinical indexes in the observation group were lower than those in the control group,with a statistically significant difference(P<0.05);There was no significant difference in the incidence of complications between the observation group and the control group(P>0.05);The levels of serum IgG,IgM and IgA in the two groups were significantly improved after operation compared with those before operation.Except that there was no statistically significant difference in the level of IgA、SCC、CA125,the levels of IgG and IgM in the observation group were higher than those in the control group,the IL-6 levels were lower than those in the control group,with a statistically significant difference(P<0.05);Follow up for 3 months after operation showed that the excellent and good rate of clinical efficacy in the observation group was significantly higher than that in the control group(P<0.05).Conclusion:Laparoscopic radical cervical resection is safe and feasible for patients with early cervical cancer,with less intraoperative blood loss,fast postoperative recovery,little impact on immune function,and good clinical effect for patients after surgery.

关 键 词：腹腔镜 根治性宫颈切除术 早期宫颈癌 效果 

分 类 号：R737.33[医药卫生—肿瘤]