苦黄针剂序贯苦黄颗粒用于治疗急性药物性肝损伤的疗效  

Curative Effect of Kuhuang Injection Sequential Kuhuang Granules in the Treatment of Acute Drug Induced Liver Injury

作　　者：陆伟[1] 王雁冰[1] 张占卿[1] LU Wei;WANG Yan-Bing;ZHANG Zhan-Qing(Department of Hepatobiliary Medicine,Shanghai Public Health Clinical Center of Fudan University,Shanghai 201508,China)

机构地区：[1]上海市公共卫生临床中心肝胆内科,上海201508

出　　处：《中国药物经济学》2022年第11期105-108,共4页China Journal of Pharmaceutical Economics

摘　　要：病毒感染所致肝损伤的发病率呈下降趋势,药物所致肝损伤的发病率有增加趋势。药物性肝损伤常见于老年患者,处方和药品数量增加可能是老年患者药物性肝损伤发生率较高的一个重要原因。本文报告了1例75岁男性患者,因多种慢性疾病长期服用多达10余种西药和中药,近期又加用中成药癃闭舒胶囊、虎力散和瘀血痹片及中药汤剂等,其中至少含有被报告有肝脏毒性的补骨脂、草乌、白鲜皮等。该患者采用苦黄针剂-颗粒序贯治疗96 d,获得了满意的疗效。The incidence of liver injury caused by viral infection is decreasing,and that caused by drugs is increasing.Drug-induced liver injury is common in elderly patients,and the increase of prescriptions and drugs may be an important cause for the higher incidence of drug-induced liver injury in elderly patients.Herein we present a 75-year-old male patient who has taken more than ten kinds of Western and Chinese medicines for a long time due to various chronic diseases.Recently,he also used Chinese patent medicines"Long Bi Shu"capsule,"Hu Li"powders and"Yu Xue Bi"tablet,and a Chinese dialectical decoction,which contain at least Fructus psoraleae,Aconitum carmichaelii,Dictamnus dasycarpus those have been reported to have liver toxicity.The patient was treated with Kuhuang injections and granules sequentially for 96 days,and a satisfactory therapeutic effect was obtained.

关 键 词：药物性肝损伤 苦黄注射液 苦黄颗粒 序贯治疗 

分 类 号：R575.5[医药卫生—消化系统] R285.6[医药卫生—内科学]