瘤床同步加量调强放疗与序贯瘤床加量调强放疗治疗乳腺癌的效果分析  

Effect Analysis of Tumor Bed Simultaneous Intensity-modulated Radiation Therapy and Sequential IntensitymodulatedRadiation Therapy for Breast Cancer

作　　者：屠婷婷[1] 陈程[1] 陈丹丹[1] 刘冰[1] Tu Ting-ting;Chen Cheng;Chen Dan-dan;Liu Bing(Department of Radiotherapy,Lianyungang Second People's Hospital,Lianyungang 222000,Jiangsu Province,China)

机构地区：[1]连云港市第二人民医院放疗科,江苏连云港222000

出　　处：《中外医药研究》2022年第11期27-29,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:比较瘤床同步加量调强放疗与序贯瘤床加量调强放疗治疗乳腺癌的临床效果。方法:选取2019年2月-2021年1月云港市第二人民医院放疗科收治的乳腺癌患者80例为观察对象,患者均接受保乳手术治疗,按照术后放疗方法不同分为瘤床组(n=38)与序贯组(n=42),瘤床组给予瘤床同步加量调强放疗治疗,序贯组给予序贯瘤床加量调强放疗治疗,比较两组患者临床疗效、放疗时间、乳房美容效果、不良反应发生率、随访3年生存率。结果:两组患者总缓解率比较,差异无统计学意义(P>0.05);瘤床组放疗时间短于序贯组,差异有统计学意义(P<0.05);两组患者乳房美容效果优良率比较,差异无统计学意义(P>0.05);两组患者不良反应发生率比较,差异无统计学意义(P>0.05);两组随访3年生存率比较,差异无统计学意义(P>0.05)。结论:瘤床同步加量调强放疗与序贯瘤床加量调强放疗治疗乳腺癌在临床疗效、乳房美容效果、不良反应及随访3年生存率并未体现出明显差异性,但瘤床同步加量调强放疗缩短了总放疗时间,综合表现较好。Objective:To compare the clinical effects of tumor bed simultaneous intensity-modulated radiation therapy and sequential intensity-modulated radiation therapy for breast cancer.Methods:Eighty patients with breast cancer admitted to the Department of Radiotherapy of the Lianyungang Second People's Hospital from February 2019 to January 2021 were selected as the observation objects.All patients received breast-conserving surgery and were divided into tumor bed group(n=38)and sequential group(n=42)according to different postoperative radiotherapy methods.The tumor bed group was treated with simultaneous IMRT,and the sequential tumor bed group was treated with sequential IMRT.The clinical efficacy,radiotherapy duration,cosmetic effect of breast,incidence of adverse reactions and 3-year survival rate were compared between the two groups.Results:There was no significant difference in the total remission rate between the two groups(P>0.05).The time of radiotherapy in tumor bed group was shorter than that in sequential group,and the difference was statistically significant(P<0.05).There was no significant difference in the rate of breast beauty effect between the two groups(P>0.05).There was no significant difference in the incidence of adverse reactions between 2 groups(P>0.05).There was no significant difference in 3-year survival rate between the two groups(P>0.05).Conclusion:There is no significant difference in clinical efficacy,breast cosmetic effect,adverse reactions and 3-year follow-up survival rate between tumor bed IMRT and sequential IMRT in the treatment of breast cancer.However,tumor bed IMRT shortened the total radiotherapy time and had a better overall performance.

关 键 词：瘤床同步加量调强放疗 序贯瘤床加量调强放疗 乳腺癌 乳房美容 

分 类 号：R73[医药卫生—肿瘤]