牙周炎与肠道菌群相关性研究进展  

Progress of research on the correlation between chronic periodontitis and intestinal flora

作　　者：谢雨桐 胡颖哲 高鹏玉 徐全臣[1,2] XIE Yutong;HU Yingzhe;GAO Pengyu;XU Quanchen(Department of Stomatology,Affiliated Hospital of Qingdao University,Qingdao 266003,China)

机构地区：[1]青岛大学附属医院口腔科,山东青岛266003 [2]青岛大学口腔医学院,山东青岛266003

出　　处：《口腔医学》2022年第11期1047-1051,共5页Stomatology

基　　金：山东省自然科学基金(ZR2020MH183)。

摘　　要：越来越多的研究表明牙周炎和肠道菌群之间关系密切。牙周炎的患者能够通过吞咽将口腔细菌转移到肠道定植,肠道原生菌群被改变,进而引发一系列肠道黏膜的免疫反应。肠道菌群失调又会导致一系列全身系统疾病,其中代表性的疾病就是炎症性肠病炎症性肠病(inflammatory bowel disease,IBD)。本文以IBD为切入点就牙周炎影响肠道菌群的可能途径以及炎症进展时、炎症得到控制后肠道菌群的变化进行综述。A growing number of studies suggest a close relationship between periodontitis and the intestinal flora.Oral bacteria swallowed by patients with chronic periodontitis could be transferred to intestinal colonization,and the primary intestinal flora is altered,thereby triggering a series of immune responses in the intestinal mucosa.Intestinal flora imbalance will lead to a series of systemic diseases,of which the representative disease is inflammatory bowel disease(IBD).Based on IBD,this article reviews the possible ways of periodontitis affecting intestinal flora and changes of intestinal flora during the progress of inflammation and after inflammation is controlled.

关 键 词：牙周炎 口腔细菌 肠道菌群 炎症性肠病 

分 类 号：R783.1[医药卫生—口腔医学]