帕金森病动作语言障碍及相关神经联动机制研究进展  

Progress in the Study of Motor Language Disorder and its Related Neural Coupling Mechanism in Parkinson Disease

作　　者：阳杨[1] 甘莉 庞子建 刘恒鑫 YANG Yang;GAN Li;PANG Zi-jian;LIU Heng-xin

机构地区：[1]成都中医药大学,成都610075 [2]成都中医药大学附属四川省八一康复中心,成都610000 [3]北京国门医院,北京100015 [4]中央民族大学,北京100176

出　　处：《中国听力语言康复科学杂志》2023年第1期61-64,共4页Chinese Scientific Journal of Hearing and Speech Rehabilitation

基　　金：成都中医药大学“杏林学者”学科人才科研提升计划(ZRQN2020023)。

摘　　要：动作语言涉及运用与动作概念有关的词汇进行语言活动的行为。在动作语言加过程中,额叶皮质会将储存的运动相关信息投射到基底节,基底节进行信息处理并与颞叶储存的概念和语义信息整合后,再投射回额叶皮质,实现动词内在动作意义激活。帕金森病的病理基础是基底节损伤,患者在早期认知功能尚可时就可能出现动作语言处理不同程度的受损。本文通过对帕金森病动作语言相关的神经基础机制研究进行回顾和总结,以期为现有的帕金森病临床语言康复提供新的思路和启示。Motor language refers to the language tasks involving the use of words related to the concept of action.In motor language processing,the frontal cortex will project the stored motion-related information to the basal ganglia,which will process the information and integrate with the conceptual and semantic information stored in the temporal lobe,and then project it back to the frontal cortex to activate the internal action meaning of verbs.The pathological basis of Parkinson’s Disease(PD)is the damage of basal ganglia,and the patients may have varying degrees of impairment in motor language processing even when they are at the early stage of this disease and with relatively intact cognitive function.This paper reviews and summarizes the research on the neural basic mechanism related to PD motor language processing disorders,to provide new ideas and enlightenment for the existing clinical speech rehabilitation of PD.

关 键 词：帕金森病 语言障碍 动作动词 基底节 额颞叶环路 

分 类 号：R742.5[医药卫生—神经病学与精神病学] R493[医药卫生—临床医学]