肺移植治疗儿童囊性纤维化1例  

Case report of lung transplantation for cystic fibrosis in a child

作　　者：郑宝英[1] 曹玲[1] Zheng Baoying;Cao Ling(Department of Respiratory,the Affiliated Children′s Hospital of Capital Institute of Pediatrics,Beijing 100020,China)

机构地区：[1]首都儿科研究所附属儿童医院呼吸内科,北京100020

出　　处：《中华实用儿科临床杂志》2022年第22期1718-1720,共3页Chinese Journal of Applied Clinical Pediatrics

摘　　要：对1例接受双肺移植手术的囊性纤维化儿童的临床及基因资料进行回顾性分析,并探讨囊性纤维化肺移植的相关问题。患儿,女,6岁余第1次就诊于首都儿科研究所附属儿童医院呼吸内科,后诊断为囊性纤维化。多年来患儿反复因肺部感染加重住院治疗,临床症状无明显改善,营养不良进行性加重,于2019年10月(17岁1个月)行双肺移植手术,目前术后2年,临床症状明显改善,生活质量明显提高,未发生移植相关并发症。提示肺移植为囊性纤维化晚期肺疾病患儿有效的治疗手段。The clinical and genetic data of a child with cystic fibrosis who received double lung transplantation were retrospectively analyzed and related problems of cystic fibrosis lung transplantation were discussed.The child was diagnosed with cystic fibrosis in the Department of Respiratory,the Affiliated Children′s Hospital of Capital Institute of Pediatrics at the age of 6 years for the first time.The patient was hospitalized repeatedly for exacerbation of pulmonary infection,with no significant clinical improvement and progressive aggravation of malnutrition.In October 2019,the patient received double lung transplantation at the age of 17 years and 1 month.Two years after surgery,the clinical symptoms and quality of life have been notably improved,and no transplant-related complications were observed.Lung transplantation is an effective treatment for children with advanced cystic fibrosis lung disease.

关 键 词：囊性纤维化 肺移植 儿童 

分 类 号：R726.5[医药卫生—儿科]