机构地区:[1]河北省石家庄市中医院,河北石家庄050051 [2]河北省辛集市妇幼保健院,河北辛集052360
出 处:《中国中医急症》2022年第12期2107-2110,共4页Journal of Emergency in Traditional Chinese Medicine
基 金:全国名中医传承工作室建设项目[国中医药办人教函(2021)270号];河北省中医药管理局课题(2020325)。
摘 要:目的 观察中药联合脐灸治疗腹泻型肠易激综合征(IBS-D)的临床疗效。方法 将120例IBS-D患者随机分为3组各40例,观察组给予口服七味白术散加味方联合脐灸治疗,对照1组口服七味白术散加味方,对照2组口服匹维溴铵联合双歧杆菌四联活菌片治疗。观察临床总有效率、治疗前后中医证候评分、生活质量水平、焦虑与抑郁评分及远期疗效。结果 观察组的总有效率为92.50%,高于对照1组和对照2组的75.00%、62.50%(P <0.05)。观察组的中医证候评分降低水平明显优于两对照组(P <0.05);观察组IBS特异性生活质量量表(IBS-QOL)评分明显优于两对照组(P <0.05);各组患者的焦虑与抑郁评分,观察组治疗后焦虑自评量表(SAS)评分明显低于两对照组(P <0.05);抑郁自评量表(SDS)评分中观察组及对照1组治疗后均比治疗前评分降低(P <0.05),观察组治疗后明显优于对照2组(P <0.05);观察组总复发率显著低于两对照组(P <0.05)。结论 中药联合脐灸治疗IBS-D能有效改善临床症状,提高生活质量,改善患者焦虑、抑郁状态,降低复发率,临床疗效显著。Objective:To explore the clinical effect of umbilical moxibustion combined with traditional Chinese medicine on diarrhea-predominant irritable bowel syndrome(IBS). Methods:A total of 120 cases of diarrheatype IBS were randomly divided into three groups:medicinal moxibustion group(observation group,n = 40),traditional Chinese medicine group(control group 1,n = 40)and western medicine group(control group 2,n = 40). The observation group was treated with Qiwei Baizhu Powder combined with umbilical moxibustion,the control group 1was treated with Qiwei Baizhu Powder,and the control group 2 was treated with pinaverium bromide tablets combined with bifidobacterium quadruple viable tablets. The total clinical effective rate,changes of TCM syndromes,quality of life,anxiety and depression scores and long-term efficacy were observed before and after treatment. Results:The total effective rate in observation group was 92.50%,which was higher than 75.00% and 62.50% in control group 1 and control group 2(P < 0.05). The TCM syndrome score of the observation group was significantly lower than that of the control groups(P < 0.05). IBS-QOL score of the observation group was significantly better than that of the control groups(P < 0.05). In the statistics of anxiety and depression scores,the SAS scores in the observation group were significantly lower than those in the control groups after treatment(P < 0.05);SDS scores of observation group and control group 1 after treatment were lower than before treatment(P < 0.05);the observation group was significantly better than control group 2 after treatment(P < 0.05). The total recurrence rate of the observation group was significantly lower than that of control groups(P < 0.05). Conclusion:Umbilical moxibustion combined with traditional Chinese medicine in the treatment of diarrhea type IBS can effectively improve the clinical symptoms,improve the quality of life,improve the patient′s anxiety and depression,reduce the recurrence rate,and the clinical effect is significant.
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