腹腔镜下子宫肌瘤切除术治疗特殊部位子宫肌瘤的疗效及对卵巢分泌功能的影响  

Effect of laparoscopic myomectomy on uterine leiomyoma at special sites and its effect on ovarian secretion function

作　　者：孔莉 Kong Li(Department of Obstetrics and Gynecology,Shandan Hospital of Traditional Chinese Medicine,Zhangye 734100,China)

机构地区：[1]山丹县中医医院妇产科,甘肃张掖734100

出　　处：《实用妇科内分泌电子杂志》2022年第18期39-41,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的分析特殊部位子宫肌瘤治疗中腹腔镜下子宫肌瘤切除术的应用价值,探究该术式对于卵巢分泌功能的影响。方法选取82例特殊部位子宫肌瘤患者,按照电脑随机数法分为对照组与研究组,每组41例。研究组实施腹腔镜下子宫肌瘤切除术治疗,对照组实施传统开腹子宫肌瘤切除术治疗。对比两组临床疗效。结果研究组手术时间长于对照组,而术中出血量少于对照组,引流管留置时间、住院时间均明显短于对照组,差异具有统计学意义(P<0.05)。手术前,两组患者促黄体生成素(LH)、卵泡刺激素(FSH)及雌二醇(E_(2))水平对比,差异无统计学意义(P>0.05);手术后,两组患者LH、FSH水平高于手术前,E_(2)水平低于手术前,且研究组患者LH、FSH水平高于对照组,E_(2)水平低于对照组,差异具有统计学意义(P<0.05)。手术前,两组患者白介素-1(IL-1)、白介素-6(IL-6)及肿瘤坏死因子7(TNF-α)对比,差异无统计学意义(P>0.05);手术后,两组IL-1、IL-6及TNF-α水平高于手术前,但研究组明显低于对照组,差异具有统计学意义(P<0.05)。结论腹腔镜下子宫肌瘤切除术治疗特殊部位子宫肌瘤具有安全性高、损伤性小、促进患者卵巢功能康复等优势,值得临床推广与应用。Objective To analyze the application value of laparoscopic myomectomy in the treatment of special uterine fibroids,and to explore the effect of this operation on ovarian secretion function.Methods 82 patients with special site uterine fibroids were selected and divided into control group and study group according to computer random number method,with 41 cases in each group.The study group was treated with laparoscopic myomectomy,while the control group was treated with traditional open myomectomy.The clinical efficacy of the two groups was compared.Results The operation time of the study group was longer than that of the control group,but the intraoperative blood loss was less than that of the control group,and the retention time of drainage tube and the length of hospital stay were significantly shorter than that of the control group,the difference was statistically significant(P<0.05).Before operation,there was no significant difference in the levels of luteinizing hormone(LH),follicle-stimulating hormone(FSH)and estradiol(E_(2))between 2 groups(P>0.05).After operation,LH and FSH levels in 2 groups were higher than before operation,E2 levels were lower than before operation,and LH and FSH levels in the study group were higher than control group,E_(2)levels were lower than control group,the difference was statistically significant(P<0.05).Before operation,there was no significant difference in interleukin-1(IL-1),interleukin-6(IL-6)and tumor necrosis factor-a(TNF-α)between 2 groups(P>0.05).After operation,the levels of IL-1,IL-6 and TNF-αin the two groups were higher than those before operation,but the levels in the study group were significantly lower than those in the control group,the difference was statistically significant(P<0.05).Conclusion Laparoscopic myomectomy for the treatment of special sites of uterine fibroids has the advantages of high safety,less damage,and promoting the recovery of ovarian function of patients,which is worthy of clinical promotion and application.

关 键 词：腹腔镜下子宫肌瘤切除术 特殊部位子宫肌瘤 卵巢分泌功能 

分 类 号：R737.33[医药卫生—肿瘤]