颈动脉钙化斑块影像的研究进展  

Research progress in imaging of carotid calcified plaque

作　　者：孙雨蒙 杨萌 胥海洋 汪振佳 于薇[1] SUN Yumeng;YANG Meng;XU Haiyang;WANG Zhenjia;YU Wei(Department of Medical Imaging,Beijing Anzhen Hospital,Capital Medical University,Beijing Institute of Heart,Lung and Blood Vessel Diseases,Beijing 100029,China;Department of Medical Imaging,Xi'an Children's Hospital,Xi'an 710002,China;Department of Radiology,Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing 100010,China)

机构地区：[1]首都医科大学附属北京安贞医院影像科,北京市心肺血管疾病研究所,北京100029 [2]西安市儿童医院影像科,西安710002 [3]首都医科大学附属北京中医院放射科,北京100010

出　　处：《磁共振成像》2023年第1期172-177,共6页Chinese Journal of Magnetic Resonance Imaging

基　　金：北京市自然科学基金(编号:7222047);中华国际医学交流基金会基金(编号:Z-2014-07-2101)。

摘　　要：颈动脉狭窄是导致缺血性脑卒中(ischemic stroke,IS)的重要原因,早发现和早治疗可显著降低其致死率和致残率。颈动脉内膜剥脱术(carotid endarterectomy,CEA)及颈动脉支架置入术(carotid artery stenting,CAS)是临床治疗颈动脉狭窄的两种血运重建方式。不稳定斑块与IS的发生密切相关。斑块成分影响斑块稳定性。然而,钙化对斑块稳定性的影响尚未被完全阐明。且既往研究大多探讨钙化的单一影像特征(如大小、数量、位置、形状、成分等)与斑块稳定性的关系,研究结果之间也存在争议。钙化作为CAS的相对禁忌证,与CAS术后并发症的发生密切相关。本文通过对既往文献进行回顾,进一步梳理钙化与斑块稳定性之间的关系以及钙化与CAS术后并发症的关系,同时提出了存在的问题及未来研究思路,旨在为该领域的研究提供参考。Carotid artery stenosis is an important cause of ischemic stroke(IS),and early detection and early treatment can significantly reduce mortality and disability.Carotid endarterectomy(CEA)and Carotid artery stenting(CAS)are two revascularization modalities for the clinical treatment of carotid artery stenosis.Unstable plaques are strongly associated with the development of IS.Plaque composition affects plaque stability.However,the effect of calcification on plaque stability has not been fully elucidated.In addition,most previous studies have explored the relationship between the single image characteristics of calcification(such as size,number,location,shape,composition,etc.)and plaque stability,and there is also controversy between the results.Calcification,as a relative contraindication to CAS,is closely related to the occurrence of postoperative complications of CAS.By reviewing the previous literature,this paper further sorts out the relationship between calcification and plaque stability,as well as the relationship between calcification and postoperative complications of CAS,and puts forward existing problems and future research ideas,aiming to provide reference for research in this field.

关 键 词：颈动脉粥样斑块 钙化斑块 斑块稳定性 颈动脉支架置入术 钙化影像 磁共振成像 计算机体层摄影血管造影 正电子发射断层显像-磁共振成像 单光子发射计算机断层成像-计算机断层显像 颈动脉血管超声 高分辨率血管壁磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R543.4[医药卫生—诊断学]