中药及其活性成分防脱生发的研究进展  

Research progress on anti-hair loss and regrowth of traditional Chinese medicine and its active ingredients

作　　者：赵海婷 郑琴 章德林 张明霞 魏韶锋 熊慧[1] 蔡可珍 吴梦琪 杨明 ZHAO Hai-ting;ZHENG Qin;ZHANG De-lin;ZHANG Ming-xia;WEI Shao-feng;XIONG Hui;CAI Ke-zhen;WU Meng-qi;YANG Ming(State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment,Key Laboratory of Modern Preparation of Traditional Chinese Medicine(TCM)Under Ministry of Education,Jiangxi University of TCM,Nanchang 330004,China;Nanchang College of Medicine,Jiangxi University of TCM,Nanchang 330004,China)

机构地区：[1]江西中医药大学现代中药制剂教育部重点实验室,创新药物与高效节能降耗制药设备国家重点实验室,江西南昌330004 [2]江西中医药大学南昌医学院,江西南昌330004

出　　处：《中草药》2022年第22期7254-7263,共10页Chinese Traditional and Herbal Drugs

基　　金：江西省重大科技研发专项(20194ABC28009);江西中医药大学科技创新团队(CXTD22006);江西中医药大学大学生创新创业训练计划项目(202110412189);江西省大学生创新创业训练计划项目(S202210412051)。

摘　　要：脱发是一种常见皮肤科疾病,与遗传、衰老、免疫、激素、感染、精神和心理等因素密切相关。中医药防治脱发历史悠久,在传统医学中有着重要意义。防治脱发的中药以补虚类、清热类和活血化瘀类为主,该类中药除具有生发、育发的药理活性外,还具有多途径、多靶点、多通路调节毛囊生长异常的特点。对补虚、清热、活血化瘀等类中药及其活性成分的防脱生发作用及其机制的研究进展进行综述,以期为脱发的预防及治疗提供理论依据和新思路,为中药防脱发产品的开发提供参考。Alopecia is a common dermatological disease closely related to genetic,aging,immune,hormonal,infectious,mental,and psychological factors.Traditional Chinese medicine has a long history of preventing and treating alopecia,and it is of great significance in traditional Chinese medicine.Traditional Chinese medicines used to prevent and treat hair loss were mainly those that tonified deficiency,cleared heat,promoted blood circulation,and eliminated blood stasis.In addition to their pharmacological activities,traditional Chinese medicines also exhibit the characteristics of regulating abnormal hair growth through multiple targets and pathways.Research progress on anti-hair loss and regrowth effects and mechanisms of traditional Chinese medicines and their active ingredients,such as tonifying deficiency,clearing heat,activating blood circulation,and removing blood stasis were reviewed in this paper,in order to provide theoretical basis and new ideas for prevention and treatment of hair loss and provide a reference for the development of traditional Chinese medicine anti-hair loss products.

关 键 词：中药 人参皂苷 黄芪甲苷 黄芩苷 槲皮苷 千金藤素 防脱生发 育发 补虚药 清热药 活血化瘀药 

分 类 号：R282.710.5[医药卫生—中药学]