低共熔溶剂提取海洋活性物质研究进展  

Advances in extracting marine active substances using deep eutectic solvents

作　　者：诸葛福照 刘晓黎 孟强 童真艺 朱曼曼 刘晨光[1] ZHUGE Fu-zhao;LIU Xiao-li;MENG Qiang;TONG Zhen-yi;ZHU Man-man;LIU Chen-guang(College of Marine Life Sciences,Ocean University of China,Qingdao 266003,China)

机构地区：[1]中国海洋大学海洋生命学院,山东青岛266003

出　　处：《海洋科学》2022年第11期147-159,共13页Marine Sciences

基　　金：山东省重点研发项目(2019GSF107031)。

摘　　要：海洋活性物质是指对生命活动有影响的海洋生物组分或代谢产物,在医药、化妆品、保健食品等领域具有广泛的应用。低共熔溶剂(deepeutecticsolvent,DES)是基于离子液体所发展而来的一种新型绿色溶剂,它具备可设计、可回收、生物相容性高、合成简易及成本低廉等多重优势,在天然活性物质的提取中具有巨大的应用前景,引起了国内外研究学者的广泛关注。本文综述了DES在海洋活性物质(包括海洋多糖、蛋白质、DNA、生物柴油、酚类和萜烯类化合物等)提取中的应用,以期为海洋活性物质的绿色提取和应用提供新的策略。Marine active substances refer to the biological components or metabolites present in marine organisms,which affect life activities and are widely used in medicine, cosmetics, health food, and other fields. As novel green solvents derived from ionic liquid, deep eutectic solvents(DESs) have many advantages, including designability,recyclability, high biocompatibility, easy synthesis, and low cost. Therefore, DESs have attracted the attention of researchers and have application prospects for extracting naturally active substances. Here, a comprehensive review on extracting marine active substances with DESs, including marine polysaccharides, proteins, DNA, biodiesel,phenolic compounds, and terpenes, is discussed to provide a new strategy for green extraction and applications for marine active substances.

关 键 词：海洋活性物质 低共熔溶剂 提取 物化特性 

分 类 号：Q5-33[生物学—生物化学]