重症脑出血患者行气管切开术后脱机序贯高流量湿化氧疗的临床疗效分析  

Clinical efficacy analysis of sequential high-flow humidified oxygen therapy weaning from ventilator after tracheotomy in patients with severe cerebral hemorrhage

作　　者：傅强 FU Qiang(Anshan Changda Hospital,Anshan 114011,China)

机构地区：[1]鞍山市长大医院,114011

出　　处：《中国实用医药》2023年第1期50-52,共3页China Practical Medicine

摘　　要：目的 分析重症脑出血患者接受气管切开术后脱机序贯高流量湿化氧疗的临床应用效果。方法 72例重症脑出血患者,按照随机数字表法分为对照组和观察组,每组36例。对照组患者接受气管切开术后脱机常规氧疗及湿化,观察组患者接受气管切开术后脱机序贯高流量湿化氧疗。比较两组患者脱机前后呼吸频率、氧合指数、动脉血二氧化碳分压及脱机后7 d内机械通气时间、重症加强护理病房(ICU)住院时间。结果 脱机前,两组患者呼吸频率、氧合指数、动脉血二氧化碳分压比较,差异无统计学意义(P>0.05);脱机后30 min、6 h、12 h、24 h,观察组患者呼吸频率均低于对照组,氧合指数均高于对照组,差异具有统计学意义(P<0.05);两组患者脱机后30 min、6 h、12 h、24 h动脉血二氧化碳分压比较,差异无统计学意义(P>0.05)。观察组患者脱机后7 d内机械通气时间为(5.51±5.36)h,ICU住院时间为(6.18±1.42)d;对照组患者脱机后7 d内机械通气时间为(12.28±9.17)h, ICU住院时间为(9.14±2.32)d。观察组患者脱机后7 d内机械通气时间及ICU住院时间均短于对照组,差异具有统计学意义(P<0.05)。结论 重症脑出血患者接受气管切开术后脱机序贯高流量湿化氧疗能够改善患者呼吸生理指标,缩短脱机后7 d内机械通气时间和ICU住院时间。Objective To analyze the clinical effect of sequential high-flow humidified oxygen therapy weaning from ventilator after tracheotomy in patients with severe cerebral hemorrhage. Methods A total of 72 patients with severe cerebral hemorrhage were randomly divided into control group and observation group, with 36 patients in each group. Patients in the control group received conventional oxygen therapy and humidification weaning from ventilator after tracheotomy, while patients in the observation group received sequential high-flow humidification oxygen therapy weaning from ventilator after tracheotomy. Both groups were compared in terms of respiratory rate, oxygenation index, arterial partial pressure of carbon dioxide, mechanical ventilation time within 7 d after weaning, and duration of intensive care unit(ICU) stay. Results Before weaning, there was no statistically significant difference in respiratory rate, oxygenation index and arterial partial pressure of carbon dioxide between the two groups(P>0.05). At 30 min, 6 h, 12 h and 24 h after weaning, the respiratory rate of patients in the observation group was lower than that of the control group, and the oxygenation index was higher than that of the control group, and the differences were statistically significant(P<0.05). There was no statistically significant difference in arterial partial pressure of carbon dioxide between the two groups at 30 min, 6 h,12 h and 24 h after weaning(P>0.05). In the observation group, the duration of mechanical ventilation within 7 d after weaning was(5.51±5.36) h, and the duration of ICU stay was(6.18±1.42) d;in the control group, the duration of mechanical ventilation within 7 d after weaning was(12.28±9.17) h, and the duration of ICU stay was(9.14±2.32) d. The duration of mechanical ventilation and duration of ICU stay in the observation group within 7 d after weaning were shorter than those in the control group, and the difference was statistically significant(P<0.05). Conclusion Sequential high-flow humidified oxygen t

关 键 词：重症脑出血 气管切开术 高流量湿化氧疗 效果 

分 类 号：R743.34[医药卫生—神经病学与精神病学] R653[医药卫生—临床医学]