从细胞生物学角度理解生物学宽度及其在口腔修复教学中的应用  

Consideration of biologic width from a cell biology perspective and its application in prosthodontics education

作　　者：张晓[1] 朱原 刘云松[2] ZHANG Xiao;ZHU Yuan;LIU Yun-song(Department of Prosthodontics,Peking University School and Hospital of Stomatology&National Clinical,Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology,Beijing 100081,China)

机构地区：[1]北京大学口腔医学院·口腔医院修复科,北京100081 [2]北京大学口腔医学院·口腔医院修复科,国家口腔医学中心,国家口腔疾病临床医学研究中心,口腔生物材料和数字诊疗装备国家工程研究中心,口腔数字医学北京市重点实验室,北京100081

出　　处：《口腔颌面修复学杂志》2023年第1期38-44,共7页Chinese Journal of Prosthodontics

基　　金：国家自然科学基金(项目编号:82170929);北京市自然科学基金(项目编号:7222224);北京大学医学部教育教学研究课题(项目编号:2022ZD05);北京市住院医师规范化培训质量提高项目(项目编号:2022-TGXM-02)。

摘　　要：生物学宽度(Biologic Width)指的是从龈沟底与牙槽嵴顶之间的恒定距离,约2 mm,其结构包括结合上皮附着及结缔组织附着。结合上皮附着和结缔组织附着都是抵御细菌侵袭的重要屏障,如果此屏障结构遭到破坏,细菌就会侵入机体内造成局部的炎症反应。生物学宽度的屏障作用是由其细胞生物学基础决定的。本文将从细胞生物学角度解析生物学宽度的概念和意义,同时也介绍了如何以生物学宽度为依据来确定牙体缺损修复方案的具体原则,旨在为牙体缺损患牙的诊治提供指导,为口腔医学生教学工作提供参考。The biologic width refers to a constant distance of approximately 2 mm between the bottom of the gingival sulcus and the top of the alveolar ridge,which structurally includes a combination of junctional epithelial attachment and fibrous connective tissue attachment.Both epithelial and connective tissue attachments are important barriers against bacterial attack.The bacteria could invade the organism and cause local inflammatory reactions if the barrier structure is disrupted.This effect of biologic width is determined by its cell biological basis.In this paper,we analyze the concept and meaning of biologic width from the perspective of cell biology and put forward a specific principle of determining the restoration plan of tooth defect based on biologic width.This article will present guidance for the diagnosis and treatment of tooth with large defect and provide a reference for clinical prosthodontics education.

关 键 词：生物学宽度 细胞生物学 口腔修复教学 

分 类 号：R78[医药卫生—口腔医学]