超广角荧光素眼底血管造影中缺血指数在视网膜血管性疾病中的应用  

Application of ischemic index of ultra-widefield fluorescein angiography in retinal vascular diseases

作　　者：蒋婧文(综述) 陈长征(审校)[1] Jiang Jingwen;Chen Changzheng(Department of Ophthalmology,Renmin Hospital of Wuhan University,Wuhan 430060,China)

机构地区：[1]武汉大学人民医院眼科中心,武汉430060

出　　处：《中华实验眼科杂志》2022年第11期1100-1103,共4页Chinese Journal Of Experimental Ophthalmology

摘　　要：荧光素眼底血管造影(FFA)是视网膜血管性疾病的重要检查方法,但传统FFA对外周视网膜的观察范围有限。超广角荧光素眼底血管造影(UWFA)是一种新兴的检查方法,扩大了视网膜观察范围,可以清晰地显示外周视网膜的病变。为了精确量化视网膜无灌注区,缺血指数(ISI)这一概念被提出。ISI即通过手动描绘UWFA图像中视网膜无灌注区域计算得出视网膜无灌注区面积与视网膜总面积的比率,是评估视网膜缺血情况的可靠指标。ISI在糖尿病视网膜病变、视网膜静脉阻塞等视网膜血管性疾病的分类、治疗和预后判断中具有重要意义。本文就ISI在视网膜血管性疾病中的应用及发展现状进行综述。Fluorescein fundus angiography(FFA)is an important examination to observe retinal vascular diseases,but the observation of peripheral retina is limited through traditional FFA.Ultra-widefield fluorescein angiography(UWFA)is a new technique which helps to expand the field of view in retina,and explores peripheral retinopathy clearly.To accurately quantify the retinal non-perfusion area,ischemic index(ISI)was proposed.It is calculated by the ratio of the retinal non-perfusion area to the total retinal area by manual description of non-perfusion area in UWFA images.As a reliable index for evaluating retinal ischemia,it is of great significance to study ISI in the classification,treatment and prognosis of retinal vascular diseases such as diabetic retinopathy(DR)and retinal vein occlusion(RVO).This article reviewed the progress in application and development of ISI in retinal vascular diseases.

关 键 词：荧光血管造影术 糖尿病视网膜病变 视网膜静脉阻塞 缺血指数 综述 

分 类 号：R774.1[医药卫生—眼科]