IOLMaster 700与IOLMaster 500不同计算公式对白内障眼人工晶状体屈光力计算的准确性比较  

A comparative study on calculation of intraocular lens power using different formulas betweenIOLMaster 700 and IOLMaster 500 in cataract eyes

作　　者：邓小慧 常平骏 黄锦海 王丹丹 赵银莹 丁锡霞 赵云娥 Deng Xiaohui;Chang Pingjun;Huang Jinhai;Wang Dandan;Zhao Yinying;Ding Xixia;Zhao Yun'e(The Eye Hospital of Wenzhou Medical University,Hangzhou 310020,China)

机构地区：[1]温州医科大学附属眼视光医院杭州院区,杭州310020 [2]宁波市第二医院眼科,宁波315010 [3]复旦大学附属眼耳鼻喉科医院,上海200031

出　　处：《中华实验眼科杂志》2022年第12期1170-1175,共6页Chinese Journal Of Experimental Ophthalmology

基　　金：浙江省重点研发计划项目(2018C03012);温州市科技局资助项目(Y2020037);浙江省医药卫生科技计划项目(2019KY111)。

摘　　要：目的比较IOLMaster 700与IOLMaster 500不同计算公式对白内障眼人工晶状体(IOL)屈光力计算的准确性。方法采用横断面研究方法,纳入2018年11月至2019年11月在温州医科大学附属眼视光医院接受白内障超声乳化摘出联合IOL植入术治疗的年龄相关性白内障患者262例262眼。分别采用IOLMaster 700和IOLMaster 500进行术前生物测量,采用IOLMaster 700和IOLMaster 500仪器内置公式Haigis、HolladayⅠ、Hoffer Q和SRK/T计算IOL屈光力。本研究以屈光预测误差为指标,比较不同眼轴长度(AL)下受检眼用2种仪器不同计算公式的屈光结果。结果在所有眼轴范围内,IOLMaster 700与IOLMaster 500 Haigis、Hoffer Q、SRK/T公式计算的绝对预测误差平均值(MAE)差异均无统计学意义(均P>0.05),IOLMaster 500 HolladayⅠ计算的MAE为0.47(0.24,0.90)D,小于IOLMaster 700的0.50(0.28,0.99)D,差异有统计学意义(Z=-3.120,P=0.002)。AL<22.0 mm、24.5 mm≤AL<26.0 mm时,4种公式计算的MAE差异均无统计学意义(均P>0.05);22.0 mm≤AL<24.5 mm时,Haigis、Hoffer Q、SRK/T公式计算的MAE差异均无统计学意义(均P>0.05),IOLMaster 500 HolladayⅠ计算的MAE为0.42(0.18,0.75)D,小于IOLMaster 700的0.45(0.25,0.79)D,差异有统计学意义(Z=-3.487,P<0.001),但差异数值很小,无临床意义;AL≥26.0 mm时,Haigis、HolladayⅠ、SRK/T公式计算的MAE差异均无统计学意义(均P>0.05);IOLMaster 500 Hoffer Q计算的MAE为0.66(0.38,1.00)D,小于IOLMaster 700的0.98(0.62,1.32)D,差异有统计学意义(Z=-3.046,P=0.002)。结论所有眼轴范围内,2种仪器Haigis、Hoffer Q和SRK/T公式屈光预测准确性接近。对于长眼轴患者,IOLMaster 700 Hoffer Q公式计算的MAE明显大于IOLMaster 500,临床使用中需谨慎。IOLMaster 700与IOLMaster 500的屈光预测准确性基本接近。Objective To compare the accuracy of IOLMaster 700 and IOLMaster 500 in intraocular lens(IOL)power calculation.Methods A cross-sectional study was conducted.Two hundred and sixty-two eyes of 262 patients who underwent phacoemulsification combined with IOL implantation at the Eye Hospital of Wenzhou Medical University from November 2018 to November 2019 were enrolled.Preoperative biometry for cataract surgery was performed using IOLMaster 700 and IOLMaster 500.IOL power was calculated through the built-in formulas,Haigis,HolladayⅠ,Hoffer Q and SRK/T of the two devices.The difference in IOL power calculation between the two devices was analyzed through the prediction error of IOL power calculation using different formulas across different axial length(AL)ranges.This study complied with the Declaration of Helsinki.The study protocol was approved by the Ethics Committee of the Eye Hospital of Wenzhou Medical University(No.2020-038-K-33).Written informed consent was obtained from each patient before the surgery.Results There was no significant difference in mean absolute error(MAE)between IOLMaster 700 and IOLMaster 500 using Haigis,Hoffer Q and SRK/T over the entire AL range(all at P>0.05).The MAE of IOLMaster 500 was 0.47(0.24,0.90)D,which was significantly lower than 0.50(0.28,0.99)D of IOLMaster 700 using HolladayⅠformula(Z=-3.120,P=0.002).When AL was<22.0 mm and≥24.5 mm-<26.0 mm,there was no significant difference in MAE between the two devices using the four formulas(all at P>0.05).When AL was≥22.0 mm-24.5 mm,there was no significant difference in the MAE between the two devices using Haigis,Hoffer Q and SRK/T(all at P>0.05),but 0.42(0.18,0.75)D from IOLMaster 500 was smaller than 0.45(0.25,0.79)D from IOLMaster 700 using HolladayⅠ,showing a statistically significant difference(Z=-3.487,P<0.001).But the difference was negligible and therefore was of no clinical significance.When AL was≥26.0 mm,there was no statistically significant difference in the MAE between the two devices using Haigis,Holladay�

关 键 词：白内障 人工晶状体 光学生物测量 屈光力 IOLMASTER 人工晶状体计算公式 

分 类 号：R779.66[医药卫生—眼科]