低剂量双源CT颅脑灌注成像在超急性期脑梗死中的诊断价值  

Diagnostic Value of Low-dose Dual-source CT Cerebral Perfusion Imaging in Hyperacute Cerebral Infarction

作　　者：孙中启 梁凤军[1] SUN Zhongqi;LIANG Fengjun(Zaozhuang City Taierzhuang District People’s Hospital,Zaozhuang 277400,China;不详)

机构地区：[1]枣庄市台儿庄区人民医院,山东枣庄277400

出　　处：《中外医学研究》2022年第36期86-89,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨超急性期脑梗死应用低剂量双源CT颅脑灌注成像(CTP)的诊断价值。方法:选取2021年1月-2022年3月枣庄市台儿庄区人民医院收治的120例疑似超急性期脑梗死患者,按照随机数字表法原则分成甲、乙、丙三组,各40例,三组均接受双源CTP检查与CT血管造影(CTA)检查,双源CTP检查中对比剂用量甲、乙、丙三组分别为70、50、30 ml。以CTA检查作为诊断金标准,对比各组疾病检出情况。结果:金标准证实85例(70.83%)为超急性期脑梗死,120例疑似患者:脑血流量轻度降低24例,中度降低80例,重度降低16例;血管狭窄情况无狭窄35例,轻度狭窄26例,中度狭窄38例,重度狭窄15例,完全闭塞6例。三组CTA检查一致率对比,差异无统计学意义(P>0.05)。三组梗死中心区灌流参数比较,差异均无统计学意义(P>0.05)。结论:针对超急性期脑梗死患者采取低剂量双源CTP检查,碘海醇对比剂剂量在30 ml左右可取得一定的效果,因此在实际检查过程可适当降低对比剂使用量,准确性也较好。Objective:To explore the diagnostic value of low-dose dual-source CT cerebral perfusion(CTP)imaging in hyperacute cerebral infarction.Method:A total of 120 patients suspected hyperacute cerebral infarction who treated in Zaozhuang City Taierzhuang District People’s Hospital from January 2021 to March 2022 were selected and divided into three groups of A,B,C by the principle of random digital table method,and 40 cases in each group.All three groups were given dual-source CTP and CT angiography(CTA),in dual-source CTP examination,the comparison agents A,B and C were 70,50 and 30 ml,respectively.Taking CTA inspection as the standard of diagnostic gold,the detection of various groups of diseases were compared.Result:Gold standard confirmed 85 cases(70.83%)as hyperacute cerebral infarction,120 suspected patients:24 cases with mild reduction of cerebral blood flow,80 cases with moderate reduction,16 cases with severe reduction;vascular stenosis:35 cases with no stenosis,26 cases with mild stenosis,38 cases with moderate stenosis,15 cases with severe stenosis,and 6 cases with complete occlusion.There was no statistically significant difference in the consistency rate of CTA among three groups(P>0.05).There were no statistically significant differences in perfusion parameters in infarct center of among three groups(P>0.05).Conclusion:For patients with hyperacute cerebral infarction,low-dose dual-source CTP examination can achieve certain effects when the dose of iodohexol contrast agent is about 30 ml.Therefore,the amount of contrast agent can be appropriately reduced in the actual examination process,has good accuracy.

关 键 词：双源CT颅脑灌注成像 低剂量 超急性期脑梗死 

分 类 号：R743.3[医药卫生—神经病学与精神病学]