人中性粒细胞防御素1-3在相关疾病中的研究进展  

Research Progress of HNP1-3 in Related Diseases

作　　者：刘小勇[1] 覃凤娴[2] 韦维[2] 韦鸿健[2] 巢薇[2] Liu Xiaoyong;Qin Fengxian;Wei Wei;Wei Hongjian;Chao Wei(Department of Laboratory Medical Science,Liuzhou Municipal Liutie Central Hospital,Liuzhou Guangxi 545007,China;Department of Laboratory Medical Science,The Fourth Affiliated Hospital of Guangxi Medical University,Liuzhou Guangxi 545005,China)

机构地区：[1]广西柳州市柳铁中心医院检验科,广西柳州545007 [2]广西医科大学第四附属医院医学检验科,广西柳州545005

出　　处：《医疗装备》2023年第2期150-154,共5页Medical Equipment

基　　金：广西壮族自治区卫生健康委员会科研课题(Z20200381);广西壮族自治区卫生健康委员会科研课题(Z20200995);广西壮族自治区卫生健康委员会科研课题(Z20190296);柳州市科技研究与技术开发计划项目(2016G020204)。

摘　　要：人中性粒细胞防御素1-3(HNP1-3)是人中性粒细胞中的一种重要机体防御素,对多种微生物具有显著的杀伤和抵御能力,其被认为与人类感染性疾病的易感性密切相关,是机体防御系统的重要组成部分。此外,HNP1-3还参与机体的免疫调节,并在肿瘤细胞抑制方面发挥重要的调控作用,在抑制多种疾病的进展方面作用重大。该研究就HNP1-3在相关疾病中的研究进展进行综述。Human neutrophil peptides 1-3(HNP1-3)is an important defensin of human neutrophils,which can significantly kill and resist a variety of microorganisms.its level is considered to be closely related to the susceptibility to human infectious diseases and is an important part of the body defense system.In addition,HNP1-3 also participates in the regulation of tumor cell inhibition and immune regulation,and plays an important role in the occurrence and development of many diseases.This article reviews the research progress of HNP1-3 in related diseases.

关 键 词：HNP1-3 相关疾病 研究进展 肿瘤 

分 类 号：R575.2[医药卫生—消化系统]