多区正向设计离焦框架镜对儿童青少年近视进展的延缓效果  

Control effect of defocus incorporated multiple segments spectacle lenses in children and adolescents’myopia

作　　者：李秀红[1] 符爱存[1] 姫娜 周路坦[3] 李光光 张凤妍[1] 吕勇[1] 王卫群[1] LI Xiuhong;FU Aicun;JI Na;ZHOU Lutan;LI Guangguang;ZHANG Fengyan;Lü Yong;WANG Weiqun(Department of Ophthalmology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan Province,China;The Affiliated Eye Hospital of Suzhou Vocational Health College,Suzhou 215000,Jiangsu Province,China;Medical Technology and Engineering Institute,Zhengzhou Railway Vocational and Technical College,Zhengzhou 450000,Henan Province,China)

机构地区：[1]郑州大学第一附属医院眼科,河南省郑州市450052 [2]苏州卫生职业技术学院附属眼视光医院,江苏省苏州市215000 [3]郑州铁路职业技术学院医学技术与工程学院,河南省郑州市450052

出　　处：《眼科新进展》2023年第1期35-39,共5页Recent Advances in Ophthalmology

基　　金：河南省教育厅高等学校重点科研项目(编号:23A320011);河南省软科学项目(编号:222400410070)。

摘　　要：目的研究多区正向设计离焦(DIMS)框架镜对儿童青少年近视进展的延缓效果。方法前瞻性临床对照研究。纳入2019年1月至2020年12月在郑州大学第一附属医院视光诊疗部就诊的近视[等效球镜度(SE)为-0.50~-6.00 D]儿童青少年276例(276眼),其中验配DIMS框架镜(DIMS组)和普通单光(SV)框架镜(SV组)者各138例,随访1年,比较两组患者的SE及眼轴长度(AL)的变化量,并使用Pearson相关分析对AL、SE变化量的影响因素进行分析。所有患者只取右眼数据纳入统计分析。结果完成6个月随访者共259例,DIMS组131例,SV组128例。戴镜6个月后DIMS组和SV组患者AL变化量分别为(0.10±0.13)mm和(0.18±0.11)mm,SE变化量分别为(-0.25±0.17)D和(-0.46±0.33)D,两组患者间AL和SE变化量相比差异均有统计学意义(均为P<0.001)。完成1年随访者共238例,DIMS组120例,SV组118例,两组中完成1年随访患者的主要基线资料差异均无统计学意义(均为P>0.05)。戴镜1年后DIMS组和SV组患者AL变化量分别为(0.22±0.16)mm和(0.38±0.21)mm,SE变化量分别为(-0.52±0.35)D和(-0.95±0.32)D,两组患者间AL和SE变化量相比差异均有统计学意义(均为P<0.001),相较于SV框架镜,DIMS框架镜延缓AL增长42.1%,延缓SE增长45.2%。Pearson相关分析结果显示,DIMS组患者戴镜1年后AL的变化量与年龄呈负相关(r=-0.252,P=0.006)。结论与SV框架镜相比,DIMS框架镜能有效延缓儿童青少年近视的进展及AL增长。Objective To study the myopia control effect of defocus incorporated multiple segments(DIMS)spectacle lenses in children and adolescents.Methods Totally 276 nearsighted children and adolescents[spherical equivalent(SE):-0.50 to-6.00 D]who were admitted to the Department of Ophthalmology,First Affiliated Hospital of Zhengzhou University from January 2019 to December 2020 were included in this prospective clinical control study,with 138 patients given DIMS spectacle lenses(DIMS group)and the other 138 patients given ordinary single vision(SV)spectacle lenses(SV group).After 1 year of follow-up,the SE and the axial length(AL)changes were compared.Pearson correlation analysis was used to analyze the influencing factors of SE and AL changes.Only the right eyes of the patients were included in the statistics.Results A total of 259 patients,131 patients in the DIMS group and 128 patients in the SV group,completed 6 months of follow-up.After 6 months,the changes in AL were(0.10±0.13)mm for the DIMS group and(0.18±0.11)mm for the SV group,respectively,and the changes in SE were(-0.25±0.17)D and(-0.46±0.33)D,respectively,and the differences in the changes of AL and SE between the two groups were statistically significant(both P<0.001).A total of 238 patients completed the 1-year follow-up,with 120 people in the DIMS group and 118 people in the SV group.There was no significant difference in the primary baseline data of the patients who completed 1-year follow-up in the two groups(all P>0.05).One year later,the changes in AL were(0.22±0.16)mm for the DIMS group and(0.38±0.21)mm for the SV group,and the changes in SE were(-0.52±0.35)D and(-0.95±0.32)D in the DIMS group and SV group,respectively,with statistically significant differences between the two groups(both P<0.001).Compared with the SV spectacle lenses,the DIMS spectacle lenses restrained the AL growth by 42.1%and controlled the SE increase by 45.2%.The Pearson correlation analysis showed that the AL change of patients in the DIMS group was negatively correla

关 键 词：多区正向设计离焦框架镜 等效球镜度 眼轴长度 近视 儿童青少年 

分 类 号：R778[医药卫生—眼科]