母乳喂养与乳腺癌病因分型的关系研究进展  

Research progress on the relationship between breast feeding and breast cancer etiological classification

作　　者：崔明秀 徐扬[2] CUI Mingxiu;XU Yang(Yangzhou University Medical Academy,Department of Obstetrics and Gynecology,Nanjing Liuhe People’s Hospital,Jiangsu Province,Nanjing 211500,China;Department of Obstetrics and Gynecology,Yangzhou Maternal and Child Care Service Centre,Jiangsu Province,Yangzhou 225007,China)

机构地区：[1]扬州大学医学院南京市六合区人民医院妇产科,江苏南京211500 [2]江苏省扬州市妇幼保健院妇产科,江苏扬州225007

出　　处：《妇儿健康导刊》2023年第2期17-20,共4页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE

基　　金：中国疾病预防控制中心妇幼保健中心母婴营养与健康研究项目(2019FYH028)。

摘　　要：乳腺癌可按照雌激素受体的状态进行分类,通过基因表达和免疫组化分为5种不同亚型:Luminal A型、Luminal B型、HER2阳性、基底细胞型和三阴性。上述五种或更多乳腺癌亚型分类可能对乳腺癌的治疗和结局有重要意义。按照ER+和ER-对乳腺癌病因进行分型在患癌风险因素的研究中更为合适。母乳喂养可降低女性患乳腺癌的风险,是女性良好的自我健康保护措施。本文就有关母乳喂养与乳腺癌病因分型关系的研究进展作一综述。Breast cancer can be classified according to the status of the estrogen receptor and are classified into five different subtypes through gene expression and immunohistochemistry:Luminal A,Luminal B,HER2-positive,basal-like,and triple negative.The five or more subtypes of breast cancer may be important implications for treatment and outcomes of breast cancer.The classification is more appropriate in the study of cancer risk factors based on ER+and ER-for breast cancer etiology.Breast feeding reduces the risk of breast cancer and is a good measure for women to protect their own health.This paper reviews the research progress on the relationship between breast feeding and etiological classification of breast cancer.

关 键 词：母乳喂养 乳腺癌 生育 ER-乳腺癌 

分 类 号：R731.9[医药卫生—肿瘤]