鞣花酸的生物活性与分析研究进展  

The biological activity and detection methods of ellagic acid

作　　者：虞唯道 刘淼[2] 宋萍[1] 沈才洪 杨雅琼 YU Weidao;LIU Miao;SONG Ping;SHEN Caihong;YANG Yaqiong(College of Food and Pharmaceutical Engineering,Nanjing Normal University,Nanjing 210023,China;Luzhou Lao Jiao Co.,Ltd.,Luzhou 646000,China;National Engineering Research Center of Solid State Brewing,Luzhou 646000,China)

机构地区：[1]南京师范大学食品与制药工程学院,江苏南京210023 [2]泸州老窖股份有限公司,四川泸州646000 [3]国家固态酿造工程技术研究中心,四川泸州646000

出　　处：《生物加工过程》2023年第1期83-90,共8页Chinese Journal of Bioprocess Engineering

基　　金：国家自然科学基金青年项目(21904064)。

摘　　要：鞣花酸(EA)是一种多酚二脂酸,属于天然多酚类物质。研究表明:EA具有很强的抗氧化能力、抗炎能力和抗癌作用,被认为是目前对癌症最有前景和最为实用的化学预防剂之一。EA的检测方式主要有高效液相色谱法(HPLC)、电化学检测法、毛细管电泳检测法以及荧光检测法。从HPLC和反相液相色谱法(RP-HPLC)两个方面,并分别从利用荧光增强检测以及利用荧光猝灭检测重点介绍EA的检测方法,以期为EA的食品分析以及生物应用提供一定的理论指导,并对将来EA的生物活性及检测方式进行了展望。Ellagic acid is a kind of polyphenol difatty acid,which is a natural polyphenolic substance.Ellagic acid has strong antioxidant capacity,anti-inflammatory and anti-cancer effect,and is widely considered as a potential chemoprevention agent against cancer.The detection methods can be divided into high performance liquid chromatography(HPLC),electrochemical detection,capillary electrophoresis and fluorescence method.Herein,the HPLC method for ellagic acid include normal phase and reverse phase.The fluorescence method was be highlighted by“turn-off”type and“turn-on”type.This article will provide a detection method to meet the food analysis and biological application.This review will comment the biological activity and detection methods of ellagic acid.

关 键 词：鞣花酸 生物活性 检测方法 荧光 色谱 

分 类 号：O629[理学—有机化学] TQ450.21[理学—化学]