半规管积水膨大仿生设计及生物力学特性研究  

Research on biomimetic design and biomechanical properties of semicircular canal hydrops swelling

作　　者：陈宇航 陈文家[1] 郭成东 王智 CHEN Yuhang;CHEN Wenjia;GUO Chengdong;WANG Zhi(College of Mechanical Engineering,Yangzhou University,Yangzhou 225127,China)

机构地区：[1]扬州大学机械工程学院,江苏扬州225127

出　　处：《实验技术与管理》2022年第12期75-79,92,共6页Experimental Technology and Management

摘　　要：通过物理仿真实验探究人体半规管因内淋巴积水膨大后对壶腹帽产生的影响。依据真实人体半规管组织切片数据,将管壁设为刚性体,利用3D打印技术制作半规管外壳。将膜迷路内的内淋巴液设为不可压缩流体,建立半规管内部流体运动微分方程;根据运动方程和实验所得配置符合本模型的内淋巴液和壶腹帽,将制得的内淋巴液和壶腹帽组装起来得到仿生半规管。根据正常半规管模型再建立不同部位膨大的模型,对所有模型先后进行脉冲加速度刺激实验和正弦刺激实验,观察壶腹帽位移状态,实验数据显示不同部位的膨大对壶腹帽的变形有着各不相同的作用。A physical simulation experiment is carried out to explore the influence of human semicircular canals on the ampulla cap due to the enlargement of endolymphatic hydrops. According to the real human semicircular canal tissue slice data, the canal wall is set as a rigid body, and the semicircular canal shell is made by 3D printing technology. The endolymph in the membranous labyrinth is set as an incompressible fluid, and a differential equation of fluid motion in the semicircular canal is established. According to the motion equation and experimental results, the endolymph and ampulla cap conforming to this model are configured. The prepared endolymph and abdominal caps are assembled to obtain the bionic semicircular canals. According to the normal semicircular canal model, different parts of the swelling model are established, and pulse acceleration stimulation experiment and sinusoidal stimulation experiment are successively performed on all models to observe the displacement state of the ampulla cap. The experimental data shows that the expansion of different parts has different effects on the deformation of the ampulla cap.

关 键 词：仿生半规管 时间常数 壶腹帽 积水膨大 频率特性 

分 类 号：Q66[生物学—生物物理学]