脂肪性肝病患者胆结石检出率及影响因素分析  

Analysis of the detectable rate of gallstones and its influencing factors in patients with fatty liver disease

作　　者：高宁[1] 李建宁[2] 邓江[1] 韩致毅[2] 吴方雄 唐海灵[4] 夏智红 鲁晓岚 GAO Ning;LI Jian-ning;DENG Jiang;XIA Zhi-hong;LU Xiao-lan(Department of Infectious Disease,the Second Affiliated Hospital of Xi'an Jiaotong University(Xi'an,710004),China;不详)

机构地区：[1]西安交通大学第二附属医院感染科,陕西西安710004 [2]克拉玛依市中心医院消化科 [3]西安医学院第一附属医院 [4]西安市中心医院消化科 [5]复旦大学附属浦东医院急诊科 [6]复旦大学附属浦东医院消化科

出　　处：《中西医结合肝病杂志》2023年第1期32-35,共4页Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases

基　　金：国家自然基金(No.82070587);上海市浦东新区卫生系统重点学科建设资助(No.PWZx2017-27);陕西省重点研发计划(No.2020SF-180);浦东医院人才课题基金(No.YJRCJJ201801)。

摘　　要：目的:拟分析脂肪性肝病(FLD)体检者胆结石检出率及影响因素,为其防治提供参考。方法:筛选克拉玛依市中心医院2016年腹部超声、年龄等资料完整的体检者,比较FLD与非FLD体检者胆结石患病率,并比较不同年龄段、体质指数、性别FLD患者胆结石检出率,用Logistic回归分析FLD体检者发生胆结石的影响因素。结果:上述资料齐全的体检者共29087人,非FLD组20167人,检出胆结石633人(3.1%);FLD组8920人,检出胆结石624人(7.0%),FLD组胆结石检出率显著高于非FLD组(P<0.001)。青年、中年及老年FLD体检者胆结石检出率分别为5.1%、8.7%及11.7%,中老年FLD患者胆结石检出率高于青年(P<0.05),但中老年之间差异无统计学意义(P>0.05),青年男性FLD患者胆结石检出率低于同年龄段女性(P<0.05),中老年男女性之间差异无统计学意义(P>0.05)。非肥胖、超重、肥胖FLD患者胆结石检出率分别为4.3%、6.8%、8.0%,超重与肥胖的FLD患者胆结石检出率无统计学差异,两者都高于非肥胖体检者(P<0.05),各BMI分层后男女性胆结石检出率差异不明显(P>0.05)。Logistic回归分析显示,年龄、体质指数是FLD体检者发生胆结石的独立影响因素。结论:FLD患者胆结石检出率较高,不同人群胆结石检出率不一,降低体质指数,可以降低FLD体检者胆结石检出率。Objective:To provide a reference for the prevention and treatment of cholelithiasis by analyzing the detectable rate of cholelithiasis and its influencing factors in physical examinees with fatty liver disease.Methods:The physical examinees with complete data,such as abdominal ultrasound,and age,in Karamay Central Hospital in 2016 were screened for analysis.The detectable rate of cholelithiasis in physical examinees with fatty liver disease and non-fatty liver disease was compared.And the detectable rate of gallstones in people with fatty liver disease of different age groups,body mass index,and gender were also compared,and the independent influencing factors of gallstones in patients with fatty liver disease were analyzed by binary Logistic regression.Results:There were a total of 29,087 physical examinees with complete physical examination data,with 20,167 people in non-fatty liver disease group and 8920 patients in the fatty liver disease group.In non-fatty liver disease group,there were 633 people with cholelithiasis(3.1%).In the fatty liver disease group,there were 624 people with cholelithiasis(7.0%).The detectable rate of cholelithiasis in the fatty liver disease group was significantly higher than that in non-fatty liver disease group(P<0.001).The detectable rate of gallstones in young,middle-aged,and elderly patients was 5.1%,8.7%,and 11.7%,respectively.The detectable rate of gallstones in middle-aged and elderly patients was higher than that in young people(P<0.05),but there was no statistically significant difference between the middle-aged and the elderly(P>0.05).The risk of gallstones in young male patients with fatty liver was lower than that in women of the same age group(P<0.05),there was no statistical significance between middle-aged and elderly men and women(P>0.05).The detectable rate of gallstones in non-obese,overweight,and obese patients with fatty liver was 4.3%,6.8%,and 8.0%,respectively.There was no statistical difference in the detectable rate of gallstones in overweight and obese pati

关 键 词：脂肪肝 胆结石 检出率 影响因素 

分 类 号：R575.1[医药卫生—消化系统]