原人参二醇组皂苷酶解产物抗2型糖尿病作用  

The protopanaxadiol saponin enzymolysis products resistance effect to type 2 diabetes mellitus

作　　者：孙航 唐金鑫 由高飞 李秋阳 徐萍 刘士伟 毕云枫[1] SUN Hang;TANG Jin-xin;YOU Gao-fei;LI Qiu-yang;XU Ping;LIU Shi-wei;BI Yun-feng(College of Food Science and Engineering,Jilin Agricultural University,Changchun 130118,Jilin,China)

机构地区：[1]吉林农业大学食品科学与工程学院,吉林长春130118

出　　处：《粮食与油脂》2023年第1期143-147,共5页Cereals & Oils

基　　金：长白山学者特聘教授专项资金项目(00566);吉林省科技厅重点科技研发项目(20180201046NY)。

摘　　要：通过建立四氧嘧啶糖尿病小鼠模型来研究原人参二醇组皂苷酶解产物(PPDEP)对2型糖尿病小鼠的治疗效果。结果表明:PPDEP可使糖耐量、血糖和MDA含量降低以及SOD活性、体重和INS含量提高;与PPD相比,PPDEP治疗糖尿病效果显著,其中中剂量组与阳性对照组差别不大。The therapeutic effect of protopanaxadiolsaponinenzymolysis product(PPDEP)on type 2 diabetes mice was studied by establishing alloxan diabetes mouse model.The results showed that PPDEP could decrease glucose tolerance,blood glucose and MDA content,and increase SOD activity,body weight and INS content.Compared with PPD,PPDEP has a significant effect on diabetes,and there was no significant difference between the middle dose group and the positive control group.

关 键 词：糖尿病小鼠模型 原人参二醇组皂苷酶解产物 2型糖尿病 

分 类 号：TS218[轻工技术与工程—粮食、油脂及植物蛋白工程]