瞬时弹性成像在慢性肝病中的临床应用  

Clinical application of transient elastography in chronic liver disease

作　　者：孔会会 张佳光[1] KONG Huihui;ZHANG Jiaguang(Department of Infection,The Third Clinical Medical College of China Three Gorges University,Yichang,Hubei 443002,China)

机构地区：[1]三峡大学第三临床医学院<国药葛洲坝中心医院>感染科,湖北宜昌443002

出　　处：《医药前沿》2022年第31期28-30,共3页Journal of Frontiers of Medicine

摘　　要：慢性肝病(CLD)是一种甚至多种损伤因素长期作用于肝脏的疾病,病理研究发现慢性肝脏疾病持续进展可导致进行性肝纤维化,此过程贯穿慢性肝病始终,继续发展可罹患肝衰竭、肝细胞癌、肝硬化失代偿等晚期不可逆性疾病。大量研究表明,肝脏瞬时弹性成像技术(TE)对肝脏硬度(LSM)及脂肪衰减参数(CAP)测定可评估纤维化程度及早期诊断非酒精性脂肪肝(NAFLD),从而及时发现肝脏纤维条索样病变及脂肪变性等病理过程,为抗肝纤维化治疗逆转疾病不良进展提供理论依据。本文就瞬时弹性在慢性肝病中的临床应用进行综述。Chronic liver disease(CLD)is a disease in which even a variety of injury factors affect the liver for a long time.A large number of studies have shown that the determination of liver stiffness(LSM)and fat attenuation parameter(CAP)by transient elastography(TE)can evaluate the degree of fibrosis and early diagnose nonalcoholic fatty liver,so as to timely discover pathological processes such as hepatic fibrous streak lesions and steatosis,and provide a theoretical basis for anti hepatic fiber therapy to reverse the adverse progress of disease.This article reviews the practical role of transient elasticity in chronic liver disease.

关 键 词：综述 肝脏瞬时弹性成像 慢性肝病 肝纤维化 脂肪衰减参数 

分 类 号：R575[医药卫生—消化系统]