Near-infrared spectroscopy muscle oximetry of patients with postural orthostatic tachycardia syndrome  

作　　者：Parvathi Kadamati Jeffrey J.Sugar Brendan J.Quirk Shima Mehrvar Gisela G.Chelimsky Harry T.Whelan Thomas C.Chelimsky Mahsa Ranji 

机构地区：[1]Biophotonics Laboratory University of Wisconsin Milwaukee Department of Electrical Engineering and Computer Science 3200 N Cramer St.,Milwaukee,WI 53211,USA [2]Medical College of Wisconsin Department of Neurology 8701 W Watertown Plank Rd,Milwaukee,WI 53226,USA [3]Medical College of Wisconsin Department of Pediatries(Gastroenterology)8701 W Waterown Plank Rd,Milwaukee,WI 53226,USA

出　　处：《Journal of Innovative Optical Health Sciences》2018年第5期21-29,共9页创新光学健康科学杂志（英文）

基　　金：UWM RGI 101×290(M.Ranji);the Bleser Endowed Chair in Neurology(H.Whelan);the Baumann Research Endowment(H.Whelan);Advancing Healthier Wisconsin grant #5520298(T.Chelimsky–PI)。

摘　　要：Postural orthostatic tachycardia syndrome(POTS)is a disabling condition characterized by orthostatic intolerance with tachycardia in the absence of drop-in blood pressure.A custom-built near-infrared spectroscopy device(NIRS)is applied to monitor the muscle oxygenation,noninvasively in patients undergoing incremental head-up tilt table(HUT).Subjects(6 POTS patients and 6 healthy controls)underwent 30 mins of 70
on a HUT.The results showed a signicant difference in deoxyhemoglobin(Hb),change-in-oxygenation(△Oxy)and blood volume(△BV)between patients and healthy controls.However,oxyhemoglobin(HbO_(2))showed a significantly faster rate of change in the healthy controls during the first 10 mins of the tilt and during the recovery.This NIRS muscle oximetry tool provides quantitative measurements of blood oxygenation monitoring in diseases such as POTS.

关 键 词：HEMOGLOBIN head-up tilt table OXYGENATION blood volume 

分 类 号：R57[医药卫生—消化系统]