A Carbonized Fluorescent Nucleolus Probe Discloses RNA Reduction in the Process of Mitophagy  

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作  者:Hua Liu Xin Geng Xin Wang Lin Wei Zhaohui Li Shen Lin Lehui Xiao 

机构地区:[1]College of Chemistry,Zhengzhou University,Zhengzhou 450001 [2]State Key Laboratory of Medicinal Chemical Biology,Tianjin Key Laboratory of Biosensing and Molecular Recognition,College of Chemistry,Nankai University,Tianjin 300071 [3]College of Chemistry and Chemical Engineering,Hunan Normal University,Changsha 410081

出  处:《CCS Chemistry》2022年第8期2698-2710,共13页中国化学会会刊(英文)

基  金:from the National Natural Science Foundation of China(NSFC,Project No.22174079,21974073).

摘  要:Mitophagy is a complicated process of cell metabolism that exhibits dynamic spatiotemporal coordination between multiple organelles.Despite its relevance to nucleoli,visualizing the distribution of nucleolar RNA in the process of mitophagy remains a great challenge because of the difficulty in specifically labeling RNA.

关 键 词:MITOPHAGY RNA nanoscopic imaging carbon dots BLINKING 

分 类 号:O657.3[理学—分析化学]

 

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