Research progress on modern pharmacological action of Radix bupleuri  

作　　者：LI Yue-yang LEI Gen-ping DONG Sheng FENG Guan-qiang 

机构地区：[1]Shaanxi University of Traditional Chinese Medicine,Xianyang 712046,China [2]Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine,Xianyang 712000,China

出　　处：《Journal of Hainan Medical University》2022年第22期66-72,共7页海南医学院学报（英文版）

基　　金：Construction Project of Inheritance Studio of Lei Genping,A Famous TCM Doctor of Shaanxi Province(Shaanxi TCM Letter[2019]No.82,Studio No.2019012);First-class Discipline Innovation Team Project of Shaanxi University of Traditional Chinese Medicine(No.2019-YL04);Xianyang Science and Technology Innovation Team Project"Clinical Innovation Team of Traditional Chinese Medicine in the Treatment of Chronic Nephritis"({2019}No.46);Shaanxi Education,Science,Culture,Health and Sports System Staff Lei Genping(Model Worker)Innovation Studio({2020}No.41)。

摘　　要：Radix bupleuri is the dried root of Umbelliferae plants Bupleurem chinense DC.or Bupleurem scorzonerifolium Willd.,which are widely distributed in Northeast China,North China,Northwest China,East China,Hubei,Sichuan and other places.The plant roots are excavated in spring and autumn and dried with removing stems and leaves and sediment.Radix bupleuri,one of the oldest and most commonly used Chinese herbal medicine,has a long history of application,with high medicinal value.Modern pharmacological studies have shown that Radix bupleuri has pharmacological effects such as anti-cancer,anti-depression,anti-inflammation,heart protection,liver protection,and kidney protection,and mainly plays an role in regulating apoptosis signaling pathway,inflammation signaling pathway,neuroendocrine system,oxidative stress signaling pathway,and fibrosis signaling pathway.This paper reviews the modern pharmacological effects of Radix bupleuri in recent years,in order to provide reference for better research,development and rational utilization of Bupleurum resources.

关 键 词：BUPLEURUM SAIKOSAPONIN Bupleurum polysaccharide Modern pharmacological action 

分 类 号：R285[医药卫生—中药学]