云南高校图书馆联盟文献共享服务平台- SAIKOSAPONIN

SAIKOSAPONIN: 作品数：18被引量：93H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：余奕杨文修赵玉英梁鸿李晓东更多>>; 相关机构：北京大学南开大学延边大学医学院附属医院延边大学更多>>; 相关期刊：《Journal of Traditional Chinese Medicine》《中国医药指南》《Chinese Herbal Medicines》《Medicinal Plant》更多>>; 相关基金：国家自然科学基金山西省自然科学基金更多>>

Research progress on modern pharmacological action of Radix bupleuri: 《Journal of Hainan Medical University》2022年第22期66-72,共7页LI Yue-yang LEI Gen-ping DONG Sheng FENG Guan-qiang; Construction Project of Inheritance Studio of Lei Genping,A Famous TCM Doctor of Shaanxi Province(Shaanxi TCM Letter[2019]No.82,Studio No.2019012);First-class Discipline Innovation Team Project of Shaanxi University of Traditional Chinese Medicine(No.2019-YL04);Xianyang Science and Technology Innovation Team Project"Clinical Innovation Team of Traditional Chinese Medicine in the Treatment of Chronic Nephritis"({2019}No.46);Shaanxi Education,Science,Culture,Health and Sports System Staff Lei Genping(Model Worker)Innovation Studio({2020}No.41)。; Radix bupleuri is the dried root of Umbelliferae plants Bupleurem chinense DC.or Bupleurem scorzonerifolium Willd.,which are widely distributed in Northeast China,North China,Northwest China,East China,Hubei,Sichuan a...; 关键词：BUPLEURUM SAIKOSAPONIN Bupleurum polysaccharide Modern pharmacological action

Integrative lipidomic and transcriptomic study unravels the therapeutic effects of saikosaponins A and D on non-alcoholic fatty liver disease被引量：30: 《Acta Pharmaceutica Sinica B》2021年第11期3527-3541,共15页Xiaojiaoyang Li Junde Ge Yajing Li Yajie Cai Qi Zheng Nana Huang Yiqing Gu Qi Han Yunqian Li Rong Sun Runping Liu; supported by grants from the National Natural Science Foundation of China(Nos.81773997 and 81073148 to Rong Sun;No.82004029 to Runping Liu;No.82004045 to Xiaojiaoyang Li);Beijing University of Chinese Medicine(No.2020-JYB-ZDGG-038 to Runping Liu,China);supported by grants from Beijing Nova Program of Science&Technology(Nos.Z201100006820025 and Z191100001119088,China);supported by research fund‘Traditional Chinese medicine pharmacology and toxicology expert(No.ts201511107)’from the Taishan Scholar Project of Shandong Province(China)。; Nonalcoholic fatty liver disease(NAFLD)has become one of the most prominent causes of chronic liver diseases and malignancies.However,few therapy has been approved.Radix Bupleuri(RB)is the most frequently used herbal ...; 关键词：SAIKOSAPONIN Nonalcoholic fatty liver disease LIPIDOME TRANSCRIPTOME Lipid metabolism

Comparative permeability of three saikosaponins and corresponding saikogenins in Caco-2 model by a validated UHPLC-MS/MS method被引量：3: 《Journal of Pharmaceutical Analysis》2021年第4期435-443,共9页Siqi Ren Jingjing Liu Yunwen Xue Mei Zhang Qiwei Liu Jie Xu Zunjian Zhang Rui Song; project was financially supported by the National Natural Science Foundation of China(No.81573626);the Open Project Program of Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards,China(No.201503);the Natural Research Foundation of Jiangsu Province,China(No.BK20161456);the Qing Lan Project of Jiangsu Province,China(2017)。; Saikosaponins(SSs)are the main active components extracted from Bupleuri Radix(BR)which has been used as an important herbal drug in Asian countries for thousands of years.It has been reported that the intestinal bact...; 关键词：Bupleuri Radix SAIKOSAPONIN Saikogenin UHPLC-MS/MS Caco-2 cells PERMEABILITY

A comparative study on different multiple cropping patterns of Bupleurum chinense被引量：2: 《Journal of Chinese Pharmaceutical Sciences》2021年第2期169-178,共10页Jiquan Liu Yu Wang Jianing Liu Xin Liu Runli He; National Natural Science Foundation of China(Grant No.31601677);Natural Science Foundation of Shanxi Province(Grant No.201701D121180);Key Research and Development Project of Jinzhong City in Shanxi Province(Grant No.Y182018);Technological innovation team of development and utilization Chinese Geoherbs Resources in Shanxi Province,China(No.2018TD009)。; Bupleurum chinense is a genuine medicinal material in Shanxi Province,and planting B.chinense is one of the main sources for local farmers to increase their income.In B.chinense cultivation,wheat-B.chinense,maize-B.ch...; 关键词：Bupleurum chinense Multiple cropping Soil nutrients Photosynthetic parameters Agronomic characteristics SAIKOSAPONIN Economic benefits

Water Extraction Process of Chinese Herbal Compound Man Gan Ning: 《Medicinal Plant》2019年第6期60-65,共6页Chunli TANG Jiangcun WEI Zhen XIE Meiyan QIU Jiabao MA Fengxian ZHAO Hongxia CHEN; Supported by Project of National Natural Science Foundation of China(81360524);Project for Improving Basic Research Ability of Middle Aged and Young Teachers in Colleges and Universities of Guangxi in 2019(2019KY0341);National Traditional Chinese Medicine Characteristic Technology Heritage Talent Training Program(20184828005);Youth Foundation Project of Guangxi University of Chinese Medicine(2019QN036);Program of Scientific Research Third-level Laboratory"Chinese(Zhuang)Medicine Chemical and Quality Analysis Laboratory"of State Administration of Traditional Chinese Medicine(Guo Zhong Yi Yao Fa 2009[21]).; [Objectives]To optimize the water extraction process of Chinese Herbal Compound Man Gan Ning and establish a method for its extraction and content determination.[Methods]The L9(34)orthogonal test was carried out,the c...; 关键词：MAN GAN Ning Orthogonal test Extraction process GINSENOSIDE RB1 Notoginsenoside R1 TANSHINONE I SAIKOSAPONIN A

Saikosaponin A induces apoptosis and upregulates autophagy in Huh7 cells: 《Journal of Hainan Medical University》2019年第2期1-5,共5页Qing-Wei Zhang Jun Bao Zhi-Long Jia Jie-Xia Sheng Er-Qing Dai; This study was supported by National Natural Science Foundation(81273745).; Objective: It is discussed whether saikosaponin A induces apoptosis of human hepatoma Huh7 cells is related to the change of autophagy level.Methods: The effects of different concentrations of SSA on proliferation and...; 关键词：SAIKOSAPONIN A(SSA) HUH7 cells AUTOPHAGY APOPTOSIS Bax PCNA LC3B BECLIN1

Polyclonal antibody preparation of BcbZIP134 for transcriptional regulation analysis on saikosaponin biosynthesis: 《Chinese Herbal Medicines》2018年第3期285-289,共5页Jiao Xu Xuan Liu Su-rui Wu Chun Sui Jian-He Wei; supported by the CAMS Innovation Fund for Medical Sciences(CIFMS)(2016-I2M-2-003);National Standardization Project of Traditional Chinese Medicine(ZYBZH-Y-JIN-34); Objective: We are trying to verify how a transcription factor BcbZIP134 regulates the synthesis of saikosaponin using specific antibody. However, it is hard to obtain this soluble protein expressed in vitro, a prerequ...; 关键词：BcbZIP134 Bupleurum chinense DC polyclonal antibody prokaryotic expression

Saikosaponin-b regulates the proliferation and apoptosis of HepG2 cells by targeting the MACC1/c-Met/Akt signaling pathway: 《中国药理学与毒理学杂志》2017年第10期965-966,共2页Xing-zhi LYU Rui-fang LI Zi-han GAO Hong-wei WANG Sang-qiang LI Jian-gang WANG; supported by Scientific and Technology Projects of Henan Province(142102310137);Science and Technology Development Project of Luoyang City(1603001A-3); OBJECTIVE Metastasis-associated in colon cancer-1(MACC1)is an oncogene that has been newly identified.It promotes tumor proliferation and invasion via the MET pathway.Our study investigated the effects of Saikosaponin...; 关键词：saikosaponin-b metastasis-associated in colon cancer-1 c-Met signaling hepatocel ular carcinoma

Identification of WRKY Transcription Factors Related to Saikosaponin Biosynthesis in Adventitious Roots of Bupleurum chinense被引量：4: 《Chinese Herbal Medicines》2017年第2期153-160,共8页Su-rui Wu Ke Gao Xuan Liu Jiao Xu Jian-he Wei Chun Sui; CAMS Innovation Fund for Medical Sciences(CIFMS)(2016-I2M-2-003); Objective To identify the genes of WRKY transcription factors（TFs） from roots of Bupleurum chinense and genes that potentially regulate saikosaponin（SS） biosynthesis.Methods Firstly,the subfamily cluster analysis ...; 关键词：adventitious roots NaCl treatment PEG treatment saikosaponins WRKY transcription factors genes

柴胡皂苷B2(Saikosaponin B2)对四氯化碳损伤HepG2细胞的保护作用被引量：2: 《中国医药指南》2014年第22期82-83,共2页崔哲沈光海; 吉林省中医药管理局项目(编号:2010-152); 目的初步探讨柴胡皂苷B2(SSB2)对CCl4肝细胞损伤的保护作用。方法用CCl4诱肝HepG2细胞损伤,设立正常对照组、CCl4损伤组和不同浓度SSB2保护组;利用四甲基偶氮唑蓝(MTT)法检测细胞活力以及流式细胞仪检测细胞周期和凋亡率的方法,观察SSB2...; 关键词：北柴胡柴胡皂苷B2 HEPG2细胞细胞凋亡肝保护作用

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

SAIKOSAPONIN

检索结果分析

下载全文

高级检索检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

SAIKOSAPONIN

检索结果分析

下载全文

用户登录

高级检索检索式检索