supported by the Natural Science Foundation of Shandong Province(No.ZR2020MH39)。
Objective:Ginsenoside Rh1(G-Rh1)has been confirmed to inhibit the growth of breast cancer and colon cancer,but its therapeutic effect on hepatocellular carcinoma(HCC)is unclear.This study investigates the therapeutic ...
supported by the grants of National Natural Science Foundation of China (No. 82104465)。
Cardiovascular and cerebrovascular diseases(CCVDs), which are circulatory system diseases caused by heart defects and vascular diseases, are the major noncommunicable diseases affecting global public health. With the ...
supported by the grants of National Natural Science Foundation of China (No. 82104465);Changchun Science & Technology Development Plan (No. 21ZGY11);the Scientific Research Planning Project of Jilin Provincial Department of Education (No. JJKH20220371KJ)。
Hepatocellular carcinoma(HCC) is one of the most prevalent malignancies globally, posing a major challenge to global health care. Protopanaxadiol ginsenosides(PDs) have been believed to significantly improve liver dis...
the National Natural Science Foundation of China(No.81973444);National Administration of Traditional Chinese Medicine High level Key Discipline Construction Project of Traditional Chinese MedicinedChemistry of Chinese Materia Medica.
Although serving as the workhorse,MS/MS cannot fully satisfy the analytical requirements of quantitative sub-metabolome characterization.Because more information intrinsically correlates to more structural and concent...
supported by the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Projects(TSBICIP-CXRC-008);Major Project of Haihe Laboratory of Synthetic Biology(E2M9560201);National Natural Science Foundation of China(32301210&31200035);the China Postdoctoral Science Foundation(No.2022M713330).
Non-alcoholic fatty liver disease(NAFLD),a type of liver disease for which no treatment is currently approved,remains a major concern worldwide.It is manifested as simple hepatocyte steatosis and can develop into infl...
supported by the grants from the National Natural Science Foundation of China(No.32101029);the Natural Science Foundation of Shandong Province(No.ZR2020QB164);the PhD Scientific Research Foundation(No.2021BKQ09);the Clinical Medical Research Foundation(No.2021wyfylcyj04);the Special Funds for Yuandu Scholars.
20(S)-Ginsenoside Rh2 has significant anti-tumor effects in various types of cancers,including human hepatocellular carcinoma(HCC).However,its molecular targets and mechanisms of action remain largely unknown.Here,we ...
supported by the National Natural Science Foundation of China(82373808);Chongqing Natural Science Foundation(cstc2021jcyj-bshX0125);Fundamental Research Funds for the Central Universities(SWURC2020001);the project for Chongqing University Innovation Research Group,Chongqing Education Committee(CXQT20006).
Objective:In this study,we aim to enhance the anti-prostate cancer efficacy of cabazitaxel(CTX)and reduce its immunosuppression and systemic toxicity by developing CTX-loaded liposomes modified with ginsenoside Rk1(Rk...
supported by the National Key Research and Development Program,China(Grant Nos.:2021YFC2101500 and 2021YFC2103900);the National Natural Science Foundation of China(Grant Nos.:22278335 and 21978236);the Natural Science Basic Research Program of Shaanxi,China(Grant No.:2023-JC-JQ-17).
The gut microbiota plays a pivotal role in the immunomodulatory and protumorigenic microenvironment of colorectal cancer(CRC).However,the effect of ginsenoside Rk3(Rk3)on CRC and gut microbiota remains unclear.Therefo...
This work was supported by an award from the Department of Science and Technology of Jilin Province(20210402043GH and 20210204063YY).
Panax ginseng C.A.Mey.is an important plant species used in traditional Chinese medicine,whose primary active ingredient is a ginsenoside.Ginsenoside biosynthesis is not only regulated by transcription factors but als...
supported by the National Natural Science Foundation of China[31872674];the Jilin Talent Development Foundation Grant[20200301018RQ];the Fundamental Research Funds for the Central Universities[CGZH202206].
Obesity-induced type 2 diabetes is mainly due to excessive free fatty acids leading to insulin resistance.Increasing thermogenesis is regarded as an effective strategy for hypolipidemia and hypoglycemia.Ginsenoside is...