女性乳腺超声背景分型与乳腺癌的关联性分析  

Correlation between ultrasound background typing of female breast and breast cancer

作　　者：赵若兰 伍小芳 张苗苗[1] 刘莹[1] 王影[1] ZHAO Ruo-lan;WU Xiao-fang;ZHANG Miao-miao;LIU Ying;WANG Ying(Department of Gland Surgery,the Second Hospital of Hebei Medical University,Shijiazhuang 050000,China)

机构地区：[1]河北医科大学第二医院腺体外科,河北石家庄050000

出　　处：《中国临床医学影像杂志》2023年第1期19-23,共5页Journal of China Clinic Medical Imaging

基　　金：国家自然科学基金资助项目(编号81974265)。

摘　　要：目的:探讨女性乳腺超声背景分型与乳腺癌之间的关联性。方法:纳入2019年1月—2021年12月河北医科大学第二医院就诊的乳腺癌300例作为观察组,非乳腺癌300例作为对照组,对所有病例采集的超声图像进行背景分型,依据美国放射学会制定的乳腺影像学报告及数据系统里提出的分型方法,并在其基础上进一步细分为均匀脂肪背景、均匀腺体背景、轻度不均匀背景、中度不均匀背景及显著不均匀背景5种分型,采用Logistic回归分析乳腺超声背景与乳腺癌的相关性。结果:年龄、初潮年龄及绝经情况影响乳腺超声背景分型。<35岁年龄组及未绝经女性乳腺的背景回声不均匀性明显更高。乳腺超声分型与乳腺癌相关(P<0.001)。对比均匀腺体背景,均匀脂肪型乳腺患乳腺癌概率增加至2.1倍;35~<45岁年龄组中,中度不均匀背景患乳腺癌的概率是它的0.3倍;≥55岁的年龄组中,轻度不均匀背景患乳腺癌的概率增加至3倍,均匀脂肪背景患乳腺癌的概率增加至4.3倍;在已绝经女性中,均匀脂肪背景患乳腺癌概率增加至3.1倍(所有P<0.05)。结论:乳腺超声背景分型与乳腺癌密切相关,乳腺癌总体相对好发于均匀脂肪型背景中,针对35~<45岁年龄组女性来说,中度不均匀背景患乳腺癌风险概率低,≥55岁年龄组女性中,轻度不均匀背景患乳腺癌风险概率较高。Objective:To inve stigate the relationship between ultrasound background typing of female breast and breast cancer.Methods:A total of 300 cases of breast cancer treated in the Second Hospital of Hebei Medical University from January 2019 to December 2021 were included as the observation group and 300 cases of non breast cancer as the control group.The ultrasound images collected from all cases were classified according to the classification method proposed in the breast imaging report and data system developed by the American College of Radiology,and on the basis of this,the ultrasound images were further divided into five types:homogeneous fat background,homogeneous gland background,slightly heterogeneous background,moderately heterogeneous background and significantly heterogeneous background.The correlation between breast ultrasound background and breast cancer was analyzed by Logistic regression.Results:The age,menarche age and menopausal status affected the background classification of breast ultrasound.The heterogeneous background in women<35 years old and premenopausal women was significantly higher.Breast ultrasound typing was associated with breast cancer(P<0.001).Compared with homogeneous gland background,the probability of breast cancer in homogeneous fat type breast increased to 2.1 times,the probability of breast cancer in the moderate heterogeneous background was 0.3 times of that in the35~<45 age group,the probability of breast cancer in the mild heterogeneous background increased to 3 times in the≥55age group,and the probability of breast cancer in the homogeneous fat background increased to 4.3 times.In the postmenopausal women,the probability of breast cancer in homogeneous fat background increased to 3.1 times(all P<0.05).Conclusion:Background classification of breast ultrasound is closely related to breast cancer.Breast cancer generally tends to occur in a homogeneous fat background.For women aged 35~<45 years old,the risk probability of breast cancer in a moderately heterogeneous background

关 键 词：乳腺肿瘤 超声检查 

分 类 号：R737.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]