脑梗死复发的相关因素  

Related factors of cerebral infarction recurrence

作　　者：邱婷婷 QIU Tingting(Department of Neurology,Guigang People's Hospital,Guangxi Zhuang Autonomous Region,Guigang537100,China)

机构地区：[1]广西壮族自治区贵港市人民医院神经内科,广西贵港537100

出　　处：《中国当代医药》2023年第4期117-120,共4页China Modern Medicine

摘　　要：目的研究脑梗死复发的相关因素,旨在为脑梗死的二级预防提供依据。方法选取2020年1月至7月贵港市人民医院收治的90例急性脑梗死患者进行回顾性分析,根据脑梗死发作次数将其分成初发组(45例)及复发组(45例)。比较两组患者的临床数据,探讨影响脑梗死复发的因素。结果单因素分析结果显示,复发组的血栓形成最大振幅(MA)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)及脑血管狭窄率均高于初发组,差异有统计学意义(P<0.05);采用多因素logistic回归分析,结果显示,MA(β=0.071,OR=1.074,95%CI=1.015~1.137)、LDL-C(β=2.275,OR=9.726,95%CI=2.302~41.093)及脑血管狭窄(β=1.342,OR=3.828,95%CI=1.246~11.763)是脑梗死复发的独立危险因素(P<0.05)。结论MA、LDL-C及脑血管狭窄是脑梗死复发独立危险因素,临床上应注意监测患者血小板功能,规范抗血小板治疗及积极进行血脂干预,降低脑梗死复发风险。Objective To study the related factors of cerebral infarction recurrence,in order to provide the basis for secondary prevention of cerebral infarction.Methods A retrospective analysis was conducted on 90 patients with acute cerebral infarction admitted to Guigang People's Hospital from January to July 2020,and they were divided into primary group(45 cases)and recurrent group(45 cases)according to the number of cerebral infarction attacks.The clinical data of the two groups were compared to explore the factors affecting cerebral infarction recurrence.Results Univariate analysis showed that the maximal amplitude of thrombosis(MA),total cholesterol(TC),low density lipoprotein cholesterol(LDL-C)and cerebrovascular stenosis rate in the recurrent group were higher than those in the primary group,and the differences were statistically significant(P<0.05).Multivariate analysis of logistic regression model showed that MA(β=0.071,OR=1.074,95%CI=1.015-1.137),LDL-C(β=2.275,OR=9.726,95%CI=2.302-41.093)and cerebrovascular stenosis(β=1.342,OR=3.828,95%CI=1.246-11.763)were independent risk factors for cerebral infarction recurrence(P<0.05).Conclusion MA,LDL-C and cerebrovascular stenosis are independent risk factors for recurrence of cerebral infarction.In clinical practice,attention should be paid to monitor platelet function of patients,standardize antiplatelet therapy and actively carry out lipid intervention to reduce the risk of recurrence of cerebral infarction.

关 键 词：复发性脑梗死 血栓最大振幅 低密度脂蛋白 脑血管狭窄 

分 类 号：R743.3[医药卫生—神经病学与精神病学]