消化内镜黏膜下剥离术治疗早期食管癌的临床效果  

Clinical Effect of Digestive Endoscopic Submucosal Dissection in the Treatment of Early-stage Esophageal Cancer

作　　者：张雅 焦志宏 邱红雨 张令 宋慧泽 陈秋杰 ZHANG Ya;JIAO Zhihong;QIU Hongyu(Zhumadian Central Hospital,Zhumadian,463000)

机构地区：[1]河南省驻马店市中心医院,463000

出　　处：《实用癌症杂志》2023年第2期248-250,共3页The Practical Journal of Cancer

摘　　要：目的探讨消化内镜黏膜下剥离术(ESD)在早期食管癌治疗中的应用价值。方法选择早期食管癌患者74例,按随机数字表法分为对照组(37例)和研究组(37例)。对照组采用内镜分片黏膜切除术(EMR),研究组予以ESD,术后均持续观察3个月。比较2组病灶切除效果、围术期指标、并发症及复发情况。结果研究组病灶整块切除率(94.59%)、病灶完全切除率(89.19%)均高于对照组(72.97%、64.86%);手术及住院时间分别为(56.48±6.72)min、(6.97±1.83)d,短于对照组的(79.35±7.01)min、(8.96±2.04)d;术中出血量、术后复发率分别为(86.32±11.46)ml、0.00%,低于对照组的(145.17±18.59)ml、16.22%,有统计学差异(P<0.05)。2组并发症相当(8.11%VS 13.51%),无统计学差异(P>0.05)。结论ESD在早期食管癌患者中具有较高的应用价值,能够彻底剥离病灶,具有手术时间短、术中出血量少的优势,有利于患者术后恢复,且复发率较低。Objective To explore the application value of digestive endoscopic submucosal dissection(ESD)in the treatment of early esophageal cancer.Methods 74 patients with early-stage esophageal cancer were divided into the control group(37 patients)and the study group(37 cases).The control group underwent endoscopic fragment mucosal resection(EMR),and the study group underwent ESD for 3 months after surgery.The effect of lesion resection,perioperative index,complications and recurrence were compared in the 2 groups.Results The whole lesion resection rate(94.59%)and the complete lesion resection rate(89.19%)were all higher than those of the control group(72.97%and 64.86%);Surgery and length of stay in the study group were(56.48±6.72)min,(6.97±1.83)d,respectively,shorter than the control group(79.35±7.01)min,(8.96±2.04)d,Intraoperative bleeding volume and postoperative recurrence rate were(86.32±11.46)ml,0.00%,respectively,Less than that of the control group,(145.17±18.59)ml,16.22%,there had statistical difference(P<0.05).The 2 groups had comparable complications(8.11%VS 13.51%),there had no statistical difference(P>0.05).Conclusion ESD has high application value in patients with early esophageal cancer.It has the advantages of short operation time and less intraoperative bleeding amount,which is conducive to postoperative recovery and low recurrence rate.

关 键 词：早期食管癌 消化内镜黏膜下剥离术 内镜分片黏膜切除术 病灶切除效果 

分 类 号：R735.1[医药卫生—肿瘤]