局部进展期胃癌围手术期治疗研究进展  

Progress of perioperative treatment for locally advanced gastric cancer

作　　者：陈佳鑫 隋红[1] CHEN Jiaxin;SUI Hong(Harbin Medical University Cancer Hospital,Heilongjiang Harbin 150040,China)

机构地区：[1]哈尔滨医科大学附属肿瘤医院,黑龙江哈尔滨150040

出　　处：《现代肿瘤医学》2023年第4期784-788,共5页Journal of Modern Oncology

摘　　要：对于初始不可切除的局部进展期胃癌患者,东西方治疗方法不尽相同,以手术为基础的多学科综合诊疗是目前的基本治疗策略。在西方国家,围手术期化疗或术后辅助放化疗是首选治疗方式;而亚洲胃D2切除术后辅助化疗是标准治疗方案,近年来,亚洲也在积极开展关于胃癌围手术期治疗的研究,虽然围手术期化疗的疗效已得到保障,但是否联合放疗、是否联合靶向治疗或免疫治疗仍未有统一标准,如何优化治疗模式和疗效预测仍是急需解决的问题。本文综述了局部进展期胃癌围手术期治疗的研究现状,并对其存在的问题及未来的发展前景进行了展望。For patients with initially unresectable locally advanced gastric cancer,the treatment methods in Eastern and Western countries are different.Surgery based multidisciplinary diagnosis and treatment is the basic treatment strategy at present.In western countries,perioperative chemotherapy or postoperative adjuvant chemoradiotherapy are the preferred treatment.In Asia,adjuvant chemotherapy after D2 gastrectomy is the standard treatment.In recent years,research on perioperative treatment of gastric cancer has been actively carried out in Asia.Although the curative effect of perioperative chemotherapy has been guaranteed,there is still no unified standard for the combination of ra⁃diotherapy,targeted therapy or immunotherapy.How to optimize the treatment mode and predict the curative effect is still an urgent problem.In this paper,the research status of perioperative treatment of locally advanced gastric cancer was reviewed,and the existing problems and future development prospects were prospected.

关 键 词：局部进展期胃癌 围手术期治疗 新辅助化疗 辅助化疗 

分 类 号：R735.2[医药卫生—肿瘤]