超声造影经直肠前列腺靶向穿刺活检术在PSA 4~10 ng/ml患者中的作用  

Effect of contrast-enhanced ultrasound transrectal targeted prostate biopsy in patients with PSA4-10 ng/ml

作　　者：秦国强 卢旭 张朝枫 罗欣 李杰贤 邹戈 江福能[2] Qin Guoqiang;Lu Xu;Zhang Chaofeng;Luo Xin;Li Jiexian;Zou Ge;Jiang Funeng(Department of Urology,Central Hospital of Panyu District,Guangzhou 511400,China;Central Laboratory of Guangzhou First People's Hospital,Guangzhou 510180,China)

机构地区：[1]番禺中心医院泌尿外科,广州511400 [2]广州市第一人民医院中心实验室,510180

出　　处：《中华腔镜泌尿外科杂志（电子版）》2023年第1期36-38,共3页Chinese Journal of Endourology(Electronic Edition)

基　　金：番禺区科技项目一般医疗卫生项目(2020-Z04-04);广州市卫生健康委员会西医类-一般引导项目(20211A010088);广州市卫生健康委员会西医类-一般引导项目(20221A011119);广州市科技计划项目基础与应用基础研究项目(202201011822)。

摘　　要：目的探讨超声造影经直肠前列腺靶向穿刺活检术(CETRUS-PB)在PSA 4~10 ng/ml患者中的作用。方法2016年1月至2018年12月,番禺中心医院82例泌尿外科收治的PSA 4~10 ng/ml的患者根据自愿原则被分入系统性经直肠超声前列腺穿刺活检术组(STRUS-PB)和CETRUS-PB组,比较两组穿刺的效率、视觉模拟疼痛评分(VAS)以及并发症。结果CETRUS-PB与STRUS-PB组在PSA 4~10 ng/ml的患者中穿刺阳性率差异无统计学意义(P=0.147),两组穿刺针数、Gleason评分以及视觉疼痛评分的比较差异有统计学意义(P<0.001),两组均未出现严重并发症。结论在PSA 4~10 ng/ml患者中,CETRUS-PB不能显著提高穿刺阳性率,但可以提高穿刺的精准度,减少穿刺针数,减轻痛苦。Objective To investigate the role of contrast-enhanced ultrasound transrectal targeted prostate biopsy(CETRUS-PB)in patients with PSA 4-10 ng/ml.Methods 82 patients with PSA 4-10 ng/ml were divided into two groups on a voluntary basis:systematic transrectal ultrasound prostate biopsy(STRUS-PB)group and CETRUS-PB group from January 2016 to December 2018 in Central Hospital of Panyu District.The biopsy efficiency,VAS and complications were compared between the two groups.Results The positive rate of STRUS-PB group and CETRUS-PB group in PSA 4-10 ng/ml patients had no significant difference(P=0.147).There was significant difference in the number of biopsy needles,Gleason score and VAS between the two groups(P<0.001).There was no serious complications in both groups.Conclusions In patients with PSA 4-10 ng/ml,CETRUS-PB can not significantly improve the positive rate of prostate biopsy compared with STRUS-PB,but it may improve the accuracy of biopsy,reduce the number of biopsy needles and reduce pain.

关 键 词：穿刺活检 前列腺癌 诊断灰区 PSA灰区 

分 类 号：R737.25[医药卫生—肿瘤] R445.2[医药卫生—临床医学]