Chitin oligosaccharides for the food industry:production and applications  

作　　者：Ran Zhang Qiong Zhao Zhenwei Yi Kaihang Zhang Jinqi Shi Liangliang Zhu Yijia Chen Jiayang Jin Liming Zhao 

机构地区：[1]State Key Laboratory of Bioreactor Engineering,East China University of Science and Technology,Shanghai 200237,China [2]Shanghai Collaborative Innovation Center for Biomanufacturing Technology(SCICBT),Shanghai 200237,China [3]Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism,School of Pharmacy,East China University of Science and Technology,130 Mei Long Road,Shanghai 200237,China

出　　处：《Systems Microbiology and Biomanufacturing》2023年第1期49-74,共26页系统微生物学与生物制造（英文）

基　　金：the National Key R&D Program of China(2019YFD0901805);the 111 Project(B18022),the Fundamental Research Funds for the Central Universities,the Open Project Funding of the State Key Laboratory of Bioreactor Engineering,ECUST(ZDXM2019);Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism(Shanghai Municipal Education Commission).

摘　　要：Chitin oligosaccharides(CHOS),high-value-added oligomers linked by N-acetyl-d-glucosamine(GlcNAc,NAG),and a small amount of d-glucosamine(GlcN,GA),have aroused increasing interest due to their excellent biological properties,including antibacterial,anti-inflammatory,and immunoprotective activities,and intestinal regulation.The efficient production and utilization of CHOS with high performance can solve problems from chitin as biowaste.However,the large-scale production of well-defined CHOS has not been fully accomplished due to the limited biotechnology and separation methods,thus impeding the research on their biological functions as well as their accurate applications.In this review,we comprehensively summarize the current preparation methods of CHOS,including the chemical,physical,enzymatic and biosynthetic methods.The advantages and disadvantages of the methods are discussed in terms of efficiency,economy,and environmental effects.Furthermore,the applications of CHOS in the food industry and their contributions to human health based on their excellent bioactivities are expounded.It is hoped that this review will help in providing new insights into the production of CHOS with high precision,and support the application of CHOS in serving the food industry as nutritional supplements or foods for special medical purposes.

关 键 词：CHITIN Chitin oligosaccharides CHITOOLIGOSACCHARIDES PRODUCTION Food applications 

分 类 号：TS201.3[轻工技术与工程—食品科学]