Top(ological-operon) secret behind the long-range transcriptional coupling  

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作  者:Lei Zhang Zhibing Wu Huasong Lu 

机构地区:[1]Department of Orthopaedic Surgery,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,Zhejiang,325000,China [2]Department of Oncology,Affiliated Zhejiang Hospital,Zhejiang University School of Medicine,Hangzhou,Zhejiang,310013,China [3]Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology,Life Sciences Institute,Zhejiang University,Hangzhou,Zhejiang,310058,China

出  处:《Signal Transduction and Targeted Therapy》2022年第11期3998-4000,共3页信号转导与靶向治疗(英文)

基  金:National Natural Science Foundation of China(grants 92053114,32070632 to H.L.and 82172679 to Z.W.);Zhejiang Provincial Natural Science Foundation of China(grant LR21C060002)to H.L.;Zhejiang Provincial Medicine and Health Science Foundation(2021KY010)to Z.W.

摘  要:In a recent study published in Nature,Levo et al.reported that paralogous genes separated by long distances are regulated by specialized DNA stretches called tethering elements,which enable their physical associations and co-dependent transcriptional coupling during Drosophila embryogenesis.

关 键 词:TRANSCRIPTIONAL COUPLING embryogenesis. 

分 类 号:Q96[生物学—昆虫学]

 

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